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Ketorolac

Generic Name
Ketorolac
Brand Names
Acular, Acuvail, Omidria, Readysharp Anesthetics Plus Ketorolac, Sprix, Toradol, Toronova Suik
Drug Type
Small Molecule
Chemical Formula
C15H13NO3
CAS Number
74103-06-3
Unique Ingredient Identifier
YZI5105V0L

Overview

Ketorolac is a Non-steroidal anti-inflammatory drug (NSAID) and is commercially available as an oral tablet, injectable, nasal spray and as an ophthalmic solution. It's analgesic properties make it a useful pain management tool across many settings including postoperative pain, rheumatoid arthritis, osteoarthritis, menstrual disorders, headaches, spinal and soft tissue pain, and ankylosing spondylitis. Impressively, ketorolac has a similar efficacy to standard doses of morphine and meperidine making it a useful opioid sparing agent.

Background

Ketorolac is a Non-steroidal anti-inflammatory drug (NSAID) and is commercially available as an oral tablet, injectable, nasal spray and as an ophthalmic solution. It's analgesic properties make it a useful pain management tool across many settings including postoperative pain, rheumatoid arthritis, osteoarthritis, menstrual disorders, headaches, spinal and soft tissue pain, and ankylosing spondylitis. Impressively, ketorolac has a similar efficacy to standard doses of morphine and meperidine making it a useful opioid sparing agent.

Indication

Ketorolac is a Non-steroidal anti-inflammatory drug (NSAID) and has antipyretic, analgesic and anti-inflammatory properties. It is indicated for short term management of acute pain that requires the calibre of pain management offered by opioids. Clinicians may choose to initiate ketorolac to manage post-operative pain, spinal and soft tissue pain, rheumatoid arthritis, osteoarthritis, ankylosing spondylitis, menstrual disorders and headaches among other ailments. Regardless of the etiology of pain, patients should use the lowest possible dose, and avoid using ketorolac for an extended period of time (ideally ≤ 5 days). A benefit of choosing ketorolac over other analgesics with similar potency is that that there does not appear to be a risk of dependence or tolerance with ketorolac use.

Associated Conditions

  • Acute Migraine
  • Eye Pain
  • Inflammation
  • Macular Edema, Cystoid
  • Ocular Itching
  • Pericarditis Acute
  • Pseudophakic Cystoid Macular Oedema
  • Severe Acute Pain
  • Acute, moderate Pain
  • Chronic aphakic cystoid macular edema
  • Intraoperative miosis
  • Postoperative ocular pain

FDA Approved Products

Ketorolac Tromethamine
Manufacturer:REMEDYREPACK INC.
Route:ORAL
Strength:10 mg in 1 1
Approved: 2025/04/18
NDC:70518-0048
Ketorolac Tromethamine
Manufacturer:Gland Pharma Limited
Route:INTRAVENOUS, INTRAMUSCULAR
Strength:15 mg in 1 mL
Approved: 2017/06/13
NDC:68083-103
Ketorolac Tromethamine
Manufacturer:Gland Pharma Limited
Route:INTRAVENOUS, INTRAMUSCULAR
Strength:30 mg in 1 mL
Approved: 2017/06/13
NDC:68083-104
ACULAR
Manufacturer:Rebel Distributors Corp.
Route:OPHTHALMIC
Strength:5 mg in 1 mL
Approved: 2009/10/20
NDC:21695-463
Ketorolac Tromethamine
Manufacturer:Lake Erie Medical DBA Quality Care Products LLC
Route:ORAL
Strength:10 mg in 1 1
Approved: 2019/07/08
NDC:35356-696

Singapore Approved Products

No Singapore products found for this drug

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