瑞波西汀

概览

Reboxetine is a drug used for the acute treatment of major depression and for maintenance therapy of depression.

作用机制

Reboxetine is a selective inhibitor of noradrenaline reuptake. It inhibits noradrenaline reuptake in vitro to a similar extent to the tricyclic antidepressant desmethylimipramine. Reboxetine does not affect dopamine or serotonin reuptake and it has low in vivo and in vitro affinity for adrenergic, cholinergic, histaminergic, dopaminergic and serotonergic receptors.

适应症

For the treatment of clinical depression.

• Major Depressive Disorder (MDD)