Polyvinyl alcohol
- Generic Name
- Polyvinyl alcohol
- Brand Names
- Clear Eyes Natural Tears, Freshkote, Minidrops, Refresh Lubricant, Stye
- Drug Type
- Small Molecule
- Chemical Formula
- -
- CAS Number
- 9002-89-5
- Unique Ingredient Identifier
- 532B59J990
- Background
Polyvinyl alcohol is a water-soluble synthetic polymer obtained by polymerization of vinyl alcohol. It has varying roles in commercial and industrial applications such as papermaking, textiles, and printing. Polyvinyl alcohol is found in ophthalmic solutions as a lubricant to prevent irritation or to relieve dryness of the eyes .
- Indication
For use as a lubricant to prevent further irritation or to relieve dryness of the eye(s) .
- Associated Conditions
- Dry Eyes
- Associated Therapies
- Eye lubrication
Comparison of drug-eluting bead transarterial chemoembolization combined with apatinib
A phase III multicenter, randomized, open-label study in China (Jan 2021-Jun 2022) evaluated DEB-TACE alone vs. DEB-TACE + apatinib for uHCC. Eligibility criteria included BCLC stage B-C, age 18-75, ECOG PS 0-1, and liver tumor <60% of total liver volume. DEB-TACE was standardized, with apatinib administered orally post-TACE. Treatment efficacy was assessed via mRECIST criteria, with PFS and OS as primary endpoints. Sample size estimation required 233 participants, with statistical analysis using Cox Frailty models to account for center effects.
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