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Carboxyamidotriazole

Generic Name
Carboxyamidotriazole
Brand Names
-
Drug Type
Small Molecule
Chemical Formula
C17H12Cl3N5O2
CAS Number
99519-84-3
Unique Ingredient Identifier
6ST3ZF52WB
Background

Carboxyamidotriazole has been used in trials studying the treatment of Lymphoma, Lung Cancer, Breast Cancer, Kidney Cancer, and Ovarian Cancer, among others.

Associated Conditions
-
Associated Therapies
-

Carboxyamidotriazole + RT in Treating Patients Newly Diagnosed Supratentorial GBM

Phase 2
Completed
Conditions
Adult Giant Cell Glioblastoma
Adult Glioblastoma
Adult Gliosarcoma
Interventions
Radiation: radiation therapy
Drug: carboxyamidotriazole
Other: pharmacological study
First Posted Date
2004-06-04
Last Posted Date
2015-05-08
Lead Sponsor
National Cancer Institute (NCI)
Target Recruit Count
55
Registration Number
NCT00004146
Locations
๐Ÿ‡บ๐Ÿ‡ธ

University of Alabama Birmingham, Birmingham, Alabama, United States

๐Ÿ‡บ๐Ÿ‡ธ

Moffitt Cancer Center, Tampa, Florida, United States

๐Ÿ‡บ๐Ÿ‡ธ

Emory University/Winship Cancer Institute, Atlanta, Georgia, United States

and more 5 locations

Carboxyamidotriazole and Ketoconazole in Treating Patients With Advanced Cancers

Phase 1
Completed
Conditions
Unspecified Adult Solid Tumor, Protocol Specific
Interventions
First Posted Date
2004-06-03
Last Posted Date
2013-02-07
Lead Sponsor
National Cancer Institute (NCI)
Target Recruit Count
30
Registration Number
NCT00003249
Locations
๐Ÿ‡บ๐Ÿ‡ธ

University of Chicago Cancer Research Center, Chicago, Illinois, United States

Carboxyamidotriazole in Treating Patients With Metastatic Kidney Cancer

Phase 2
Completed
Conditions
Recurrent Renal Cell Cancer
Stage IV Renal Cell Cancer
Interventions
First Posted Date
2003-07-28
Last Posted Date
2013-01-16
Lead Sponsor
National Cancer Institute (NCI)
Target Recruit Count
335
Registration Number
NCT00006486
Locations
๐Ÿ‡บ๐Ÿ‡ธ

Cancer and Leukemia Group B, Chicago, Illinois, United States

Carboxyamidotriazole in Treating Patients With Refractory or Recurrent Ovarian Epithelial, Fallopian Tube, or Primary Peritoneal Cancer

Phase 2
Completed
Conditions
Fallopian Tube Cancer
Ovarian Cancer
Primary Peritoneal Cavity Cancer
First Posted Date
2003-01-27
Last Posted Date
2013-06-20
Lead Sponsor
National Cancer Institute (NCI)
Registration Number
NCT00019461
Locations
๐Ÿ‡บ๐Ÿ‡ธ

Warren Grant Magnuson Clinical Center - NCI Clinical Studies Support, Bethesda, Maryland, United States

Carboxyamidotriazole in Treating Patients With Stage III or Stage IV Non-small Cell Lung Cancer

Phase 3
Completed
Conditions
Stage IIIB Non-small Cell Lung Cancer
Stage IV Non-small Cell Lung Cancer
Stage IIIA Non-small Cell Lung Cancer
Interventions
Drug: carboxyamidotriazole
Other: placebo
Procedure: quality-of-life assessment
Other: laboratory biomarker analysis
First Posted Date
2003-01-27
Last Posted Date
2014-05-20
Lead Sponsor
National Cancer Institute (NCI)
Target Recruit Count
186
Registration Number
NCT00003869
Locations
๐Ÿ‡บ๐Ÿ‡ธ

North Central Cancer Treatment Group, Rochester, Minnesota, United States

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