Efavirenz
- Generic Name
- Efavirenz
- Brand Names
- Atripla, Stocrin, Sustiva, Symfi, Efavirenz Teva
- Drug Type
- Small Molecule
- Chemical Formula
- C14H9ClF3NO2
- CAS Number
- 154598-52-4
- Unique Ingredient Identifier
- JE6H2O27P8
- Background
Efavirenz (brand names Sustiva® and Stocrin®) is a non-nucleoside reverse transcriptase inhibitor (NNRTI) and is used as part of highly active antiretroviral therapy (HAART) for the treatment of a human immunodeficiency virus (HIV) type 1.
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- Indication
For use in combination treatment of HIV infection (AIDS)
- Associated Conditions
- Human Immunodeficiency Virus Type 1 (HIV-1) Infection
- Associated Therapies
- -
Interaction With HIV Antiretroviral Agents
- Conditions
- Interventions
- First Posted Date
- 2015-09-22
- Last Posted Date
- 2017-12-06
- Lead Sponsor
- Bayer
- Target Recruit Count
- 40
- Registration Number
- NCT02556268
SSAT063- Pharmacokinetics of Efavirenz 400 mg Once Daily During Pregnancy in HIV-1 Infected Women
- Conditions
- Interventions
- First Posted Date
- 2015-07-16
- Last Posted Date
- 2017-10-20
- Lead Sponsor
- St Stephens Aids Trust
- Target Recruit Count
- 26
- Registration Number
- NCT02499874
- Locations
- 🇬🇧
St Stephen's Centre, Chelsea and Westminster Hospital, London, United Kingdom
Efficacy, Safety and Optimal Dose of VM-1500 in Comparison to Efavirenz Added to Standard-of-care Antiretroviral Therapy
- Conditions
- Interventions
- First Posted Date
- 2015-07-03
- Last Posted Date
- 2018-09-25
- Lead Sponsor
- Viriom
- Target Recruit Count
- 150
- Registration Number
- NCT02489461
- Locations
- 🇷🇺
Moscow Prevention AIDS Center, Moscow, Russian Federation
🇷🇺Lipetsk regional center for AIDS prevention, Lipetsk, Lipetsk Region, Russian Federation
🇷🇺Perm Regional center for AIDS prevention, Perm, Perm Region, Russian Federation
Efficacy of VHM After Treatment Interruption in Subjects Initiating ART During Acute HIV Infection
- Conditions
- Interventions
- First Posted Date
- 2015-06-19
- Last Posted Date
- 2023-06-22
- Lead Sponsor
- SEARCH Research Foundation
- Target Recruit Count
- 15
- Registration Number
- NCT02475915
- Locations
- 🇹🇭
SEARCH, the Thai Red Cross AIDS Research Centre, Bangkok, Thailand
Risk of CV Events With EFV vs. EFV-free Regimens
- First Posted Date
- 2015-04-27
- Last Posted Date
- 2015-04-27
- Lead Sponsor
- Bristol-Myers Squibb
- Target Recruit Count
- 29612
- Registration Number
- NCT02426866
Influence of Cytochrome P2B6 on Efavirenz Dose in HIV-infected Thai Patients
- First Posted Date
- 2015-04-20
- Last Posted Date
- 2015-08-04
- Lead Sponsor
- Mahidol University
- Target Recruit Count
- 190
- Registration Number
- NCT02421289
- Locations
- 🇹🇭
Faculty of medicine Ramathibodi Hospital, Bangkok, Thailand
PK TDF in Thai HIV-infected Children
- Conditions
- Interventions
- First Posted Date
- 2015-03-31
- Last Posted Date
- 2015-03-31
- Target Recruit Count
- 32
- Registration Number
- NCT02404259
- Locations
- 🇹🇭
Khon Kaen University, Khon Kaen, Thailand
CYP2B6 Genetics and Drug Interactions in Healthy Volunteers
- Conditions
- Interventions
- First Posted Date
- 2015-03-27
- Last Posted Date
- 2017-10-11
- Lead Sponsor
- Indiana University
- Target Recruit Count
- 70
- Registration Number
- NCT02401256
- Locations
- 🇺🇸
Indiana University School of Medicine, Indianapolis, Indiana, United States
Sleep and Cognition After Atripla to Stribild Switch
- First Posted Date
- 2014-11-05
- Last Posted Date
- 2016-03-14
- Lead Sponsor
- University of Hawaii
- Target Recruit Count
- 30
- Registration Number
- NCT02283060
- Locations
- 🇺🇸
Hawaii Center for AIDS, Honolulu, Hawaii, United States
A Study to Evaluate the Effects of Genetic Factors on the Pharmacokinetics of Antiretroviral Drugs During Pregnancy and Lactation
- First Posted Date
- 2014-10-21
- Last Posted Date
- 2017-09-06
- Lead Sponsor
- Adeniyi Olagunju
- Target Recruit Count
- 460
- Registration Number
- NCT02269462
- Locations
- 🇳🇬
St Monica's Hospital, Adikpo, Benue State, Nigeria
🇳🇬Bishop Murray Medical Centre, Makurdi, Benue State, Nigeria
🇳🇬St Mary's Hospital, Okpoga, Benue State, Nigeria
Drug Development Updates
Stay informed with timely notifications on clinical trials, regulatory changes, and research advancements related to this medication.