破伤风免疫球蛋白 (Hypertet)

概览

Tetanus immune globulin is a solution of antibodies used to prevent tetanus after an injury.

作用机制

The immune globulin binds to tetanus toxiod, interfering with the normal interaction of the toxoid with human tissue. This prevents the toxoid from invading the nervous system and producing painful muscle spasms as well as autonomic dysfunction . The Clostridium tetani bacterium is killed either via antibiotic treatment of the host's immune system and immune globulin-bound toxoid is likely broken down by phagocytic immune cells.

适应症

For use as prophylaxis against tetanus in patients who are injured and have incomplete of uncertain immunization status . May also be used in the treatment of active tetanus.

• Tetanus