Rocuronium
- Generic Name
- Rocuronium
- Brand Names
- -
- Drug Type
- Small Molecule
- Chemical Formula
- C32H53N2O4
- CAS Number
- 143558-00-3
- Unique Ingredient Identifier
- WRE554RFEZ
- Background
Rocuronium (rapid onset-curonium) is a desacetoxy analogue of vecuronium with a more rapid onset of action. It is an aminosteroid non-depolarizing neuromuscular blocker or muscle relaxant used in modern anaesthesia, to facilitate endotracheal intubation and to provide skeletal muscle relaxation during surgery or mechanical ventilation. Introduced in 1994, ro...
- Indication
For inpatients and outpatients as an adjunct to general anesthesia to facilitate both rapid sequence and routine tracheal intubation, and to provide skeletal muscle relaxation during surgery or mechanical ventilation.
- Associated Conditions
- Muscle fasciculation caused by succinylcholine
- Associated Therapies
- Curarization therapy, Neuromuscular blocking therapy, Facilitation of small bowel intubation therapy
Rapid Sequence Intubation With Magnesium-rocuronium Compared With Succinylcholine - A Randomised Clinical Study
- Conditions
- Interventions
- First Posted Date
- 2012-04-05
- Last Posted Date
- 2015-07-20
- Lead Sponsor
- University Hospital, Geneva
- Target Recruit Count
- 280
- Registration Number
- NCT01571908
- Locations
- 🇨🇭
University Hospital of Geneva, Anesthesia Department, Geneva, Canton of Geneva, Switzerland
🇨🇭Division of Anaesthesiology, University Hospital of Lausanne (CHUV), Lausanne, Vaud, Switzerland
The Effect of Priming Intravenous Rocuronium on Fentanyl-Induced Coughing
- First Posted Date
- 2012-02-14
- Last Posted Date
- 2012-02-14
- Lead Sponsor
- Taichung Armed Forces General Hospital
- Target Recruit Count
- 260
- Registration Number
- NCT01532466
- Locations
- 🇨🇳
Taichung Armed Forces General Hospital, Taichung, Taiwan
The Muscle Relaxation-study
- First Posted Date
- 2012-02-01
- Last Posted Date
- 2014-04-21
- Lead Sponsor
- Herlev Hospital
- Target Recruit Count
- 49
- Registration Number
- NCT01523886
- Locations
- 🇩🇰
Department of anesthesia and department of gastro-intestinale diseases, Aleris-Hamlet, Soeborg, Denmark
Comparison of Methods to Facilitate Rapid Sequence Intubation
- Conditions
- Interventions
- First Posted Date
- 2011-11-24
- Last Posted Date
- 2012-08-27
- Lead Sponsor
- Seoul National University Bundang Hospital
- Target Recruit Count
- 110
- Registration Number
- NCT01479751
- Locations
- 🇰🇷
Seoul National University Bundang hopital, Seongnam, Gyeonggi-Do, Korea, Republic of
Optimal Dose of Succinylcholine and Rocuronium for Electroconvulsive Therapy (ECT)
- Conditions
- Interventions
- First Posted Date
- 2011-09-28
- Last Posted Date
- 2015-06-02
- Lead Sponsor
- Massachusetts General Hospital
- Target Recruit Count
- 45
- Registration Number
- NCT01441960
- Locations
- 🇺🇸
Massachusetts General Hospital, Boston, Massachusetts, United States
Desflurane Versus Propofol in the Sitting Position
- Conditions
- Interventions
- First Posted Date
- 2011-09-20
- Last Posted Date
- 2013-09-09
- Lead Sponsor
- Gachon University Gil Medical Center
- Target Recruit Count
- 40
- Registration Number
- NCT01436799
SPME For Metabolomics And Concomitant Measurements Of Rocuronium Bromide Levels In Liver Transplantation
- First Posted Date
- 2011-07-28
- Last Posted Date
- 2015-04-24
- Lead Sponsor
- University Health Network, Toronto
- Target Recruit Count
- 28
- Registration Number
- NCT01404793
- Locations
- 🇨🇦
Toronto General Hospital, Toronto, Ontario, Canada
Impact of Anesthetic Choice (Sevoflurane Versus Desflurane) on Airway Reflex Recovery in the Context of Antagonized Neuromuscular Block
- First Posted Date
- 2010-09-10
- Last Posted Date
- 2014-05-16
- Lead Sponsor
- University of California, San Francisco
- Target Recruit Count
- 107
- Registration Number
- NCT01199237
- Locations
- 🇺🇸
UCSF Moffitt-Long Hospital, San Francisco, California, United States
🇺🇸UCSF Helen Diller Cancer Center, San Francisco, California, United States
Electromyographic (EMG) on the Anaesthesia Monitor
- Conditions
- First Posted Date
- 2010-06-11
- Last Posted Date
- 2010-06-11
- Lead Sponsor
- Tampere University Hospital
- Target Recruit Count
- 30
- Registration Number
- NCT01142635
- Locations
- 🇫🇮
Tampere University Hospital, Tampere, Finland
Study of Efficacy, Pharmacokinetics and Safety of Continuous Intravenous Infusion of Org 9426 (Study P05977)
- Conditions
- Interventions
- First Posted Date
- 2009-10-02
- Last Posted Date
- 2015-05-12
- Lead Sponsor
- Merck Sharp & Dohme LLC
- Target Recruit Count
- 38
- Registration Number
- NCT00988520
Drug Development Updates
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