Vitamin A

Generic Name: Vitamin A

Brand Names: Aquasol A, Infuvite, Infuvite Pediatric, Mvc-fluoride, Mvi Pediatric, Vitafol-one

Drug Type: Small Molecule

Chemical Formula: C_₂₀H_₃₀O

CAS Number: 68-26-8

Unique Ingredient Identifier: G2SH0XKK91

Background: Retinol and derivatives of retinol that play an essential role in metabolic functioning of the retina, the growth of and differentiation of epithelial tissue, the growth of bone, reproduction, and the immune response. Dietary vitamin A is derived from a variety of carotenoids found in plants. It is enriched in the liver, egg yolks, and the fat component of d...

Indication: For the treatment of vitamin A deficiency.

Associated Conditions: Deficiency, Vitamin A, Deficiency, Vitamin D, Degenerative Retinal Disorders, Disorder of the Epithelium, Disorder of the Mesoderm, Inner ear disorder, Vitamin Deficiency, Vitamin E Deficiency

Associated Therapies: Nutritional supplementation

Clinical Trials

Vitamin A and D Supplementation in Allogeneic HCT

Phase 2

Recruiting

Conditions: Acute Lymphoblastic Leukemia
Lymphoblastic Lymphoma
Myelodysplastic Syndromes
Biphenotypic Acute Leukemia
Myeloprolipherative Neoplsm
Non-hodgkin Lymphoma
Acute Myeloid Leukemia
Chronic Myeloid Leukemia

Interventions: Drug: Vitamin A
Drug: Vitamin D3

First Posted Date: 2024-07-18

Last Posted Date: 2024-07-31

Lead Sponsor: St. Petersburg State Pavlov Medical University

Target Recruit Count: 220

Registration Number: NCT06508099

Locations: 🇷🇺
RM Gorbacheva Research Institute, Saint Petersburg, Russian Federation

Vitamin A Supplementation in Allogeneic Stem Cell Transplantation.

Phase 2

Not yet recruiting

Conditions: Graft Vs Host Disease
Vitamin A Deficiency
Vitamin D Deficiency

Interventions: Drug: Vitamin A
Other: Placebo

First Posted Date: 2024-06-10

Last Posted Date: 2024-11-06

Lead Sponsor: Children's Hospital Medical Center, Cincinnati

Target Recruit Count: 190

Registration Number: NCT06450925

Locations: 🇺🇸
Moffitt Cancer Center, Tampa, Florida, United States
🇺🇸
The Ohio State University, Columbus, Ohio, United States
🇺🇸
Roswell Park Comprehensive Cancer Center, Buffalo, New York, United States

Quintuple Method for Treatment of Multiple Refractory Colorectal Liver Metastases

Phase 2

Not yet recruiting

Conditions: For Patients With Colorectal Cancer Liver Metastases Who Were Not Able to Curative Surgical Resection.Focused on the Treatment Effect With the Quintuple Method

Interventions: Drug: Oxaliplatin
Drug: S1
Drug: Cetuximab
Drug: Metronidazole
Drug: Vitamin A
Drug: Folic acid

First Posted Date: 2023-03-20

Last Posted Date: 2023-03-20

Lead Sponsor: Liaoning Tumor Hospital & Institute

Target Recruit Count: 100

Registration Number: NCT05774964

Locations: 🇨🇳
Liaoning Tumor Hospital & Institute, Shenyang, Liaoning, China

Early Blocking Strategy for Metachronous Liver Metastasis of Colorectal Cancer Based on Pre-hepatic CTC Detection

Phase 2

Not yet recruiting

Conditions: Preventive Effect of Quintuple Therapy on Metachronous Liver Metastases in Patients With Colorectal Cancer

Interventions: Drug: Oxaliplatin
Drug: S1
Drug: Capecitabine
Drug: Cetuximab
Drug: Metronidazole
Drug: Vitamin A
Drug: Folic acid

First Posted Date: 2023-02-09

Last Posted Date: 2023-02-09

Lead Sponsor: Liaoning Tumor Hospital & Institute

Target Recruit Count: 100

Registration Number: NCT05720559

Pilot Trial of Supplemental Vitamin A and Nicotinamide

Early Phase 1

Not yet recruiting

Conditions: Skin Cancer
Kidney Transplant Recipients

Interventions: Drug: Vitamin A
Drug: Nicotinamide

First Posted Date: 2023-01-27

Last Posted Date: 2023-01-27

Lead Sponsor: Rhode Island Hospital

Target Recruit Count: 30

Registration Number: NCT05702398

Olfactory and Neurosensory Rehabilitation in COVID-19-related Olfactory Dysfunction

Phase 2

Conditions: Coronavirus Disease 2019

Interventions: Device: Electronic portable aromatic rehabilitation (EPAR) diffuser
Drug: Vitamin A

First Posted Date: 2021-05-25

Last Posted Date: 2021-05-25

Lead Sponsor: Ivan FN Hung MD

Target Recruit Count: 25

Registration Number: NCT04900415

Locations: 🇭🇰
Pamela Youde Nethersole Eastern Hospital, Hong Kong, Hong Kong
🇭🇰
The University of Hong Kong, Queen Mary Hospital, Hong Kong, Hong Kong

Efficacy and Safety of Vitamin A Treatment for Children With Sepsis

Not Applicable

Conditions: Vitamin A Deficiency
Pediatric
Sepsis

Interventions: Drug: Oil
Drug: Vitamin A

First Posted Date: 2019-10-16

Last Posted Date: 2022-01-04

Lead Sponsor: West China Hospital

Target Recruit Count: 450

Registration Number: NCT04127968

The Correlation Between Vitamin A / E Levels and Preeclampsia

Not Applicable

Conditions: Preeclampsia
Vitamin A Deficiency
Vitamin E Deficiency

Interventions: Drug: Vitamin A
Drug: Vitamin E

First Posted Date: 2019-06-03

Last Posted Date: 2019-06-03

Lead Sponsor: Second Affiliated Hospital, School of Medicine, Zhejiang University

Target Recruit Count: 300

Registration Number: NCT03971604

Locations: 🇨🇳
The second affiliated hospital of medical college of zhejiang university, Hangzhou, Zhejiang, China

Effects of Early Vitamin A Supplementation on the Risk for Retinopathy of Prematurity in Extremely Preterm Infants

Not Applicable

Completed

Conditions: Retinopathy of Prematurity

Interventions: Drug: Vitamin A

First Posted Date: 2017-05-16

Last Posted Date: 2018-09-05

Lead Sponsor: Huiqing Sun

Target Recruit Count: 262

Registration Number: NCT03154723

Locations: 🇨🇳
Zhengzhou Children's Hospital, Zhengzhou, Henan, China

Effects of Retinoids on CYP2D6 Activity During Pregnancy

Phase 1

Completed

Conditions: CYP2D6 Polymorphism

Interventions: Drug: Vitamin A

First Posted Date: 2017-04-18

Last Posted Date: 2022-11-04

Lead Sponsor: University of Washington

Target Recruit Count: 82

Registration Number: NCT03117660

Locations: 🇺🇸
University of Washington, Seattle, Washington, United States

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