Vitex agnus-castus fruit extract
- Generic Name
- Vitex agnus-castus fruit extract
- Drug Type
- Biotech
- Unique Ingredient Identifier
- 433OSF3U8A
Overview
Vitex agnus-castus fruit extract is obtained from dry fruits of Vitex agnus-castus. The fruits contain mixture of iridoids, flavonoids and compounds in leaves and flowers that structurally resemble sex hormones. Clinical studies demonstrates effectiveness of vitex agnus-castus fruit extract in the management of premenstrual stress syndrome (PMS) and cyclical breast pain (mastalgia). The main mechanism of action of vitex agnus-castus fruit extract has not been fully elucidated, however it is suggested to modulate the stress-induced prolactin secretion via dopaminergic actions, and μ (mu) - and δ (delta) -opioid receptors.
Background
Vitex agnus-castus fruit extract is obtained from dry fruits of Vitex agnus-castus. The fruits contain mixture of iridoids, flavonoids and compounds in leaves and flowers that structurally resemble sex hormones. Clinical studies demonstrates effectiveness of vitex agnus-castus fruit extract in the management of premenstrual stress syndrome (PMS) and cyclical breast pain (mastalgia). The main mechanism of action of vitex agnus-castus fruit extract has not been fully elucidated, however it is suggested to modulate the stress-induced prolactin secretion via dopaminergic actions, and μ (mu) - and δ (delta) -opioid receptors.
Indication
No indication information available.
Associated Conditions
- Breast Pain
- Menstrual Cycle Abnormal
- Premenstrual Syndrome (PMS)
Clinical Trials
Title | Posted | Study ID | Phase | Status | Sponsor |
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No clinical trials found
No clinical trials found for this drug
FDA Approved Products
Product Name | Manufacturer | Route | Strength | Approved | NDC Code |
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No FDA products found
No FDA products found for this drug
EMA Approved Products
Medicine Name | EMA Number | Auth. Holder | Country | Drug Type | Status | Issued | Opinion | Revision |
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No EMA products found
No EMA products found for this drug
HSA Approved Products
Product Name | Manufacturer | Dosage Form | Strength | Approved | Approval No. |
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No HSA products found
No HSA products found for this drug
NMPA Approved Products
Product Name | Approval No. | Manufacturer | Dosage Form | Trade Name | Strength | Type | Status | Date | Import |
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No NMPA products found
No NMPA products found for this drug
PPB Approved Products
Product Name | Registration Code | Company | Category | Sale Type | Reg. Date |
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No PPB products found
No PPB products found for this drug
TGA Approved Products
Product Name | ARTG ID | Sponsor | Status | Reg. Date | Ingredient |
|---|---|---|---|---|---|
369430 | Active | 2021/06/16 | Vitex agnus-castus | ||
447973 | Active | 2024/05/07 | Vitex agnus-castus | ||
405182 | Active | 2023/02/21 | Vitex agnus-castus | ||
409292 | Active | 2023/05/22 | Vitex agnus-castus | ||
375423 | Active | 2021/09/28 | Vitex agnus-castus | ||
395854 | Active | 2022/09/12 | Vitex agnus-castus | ||
426712 | Pharmametics Products A Division of Max Biocare Pty Ltd | Active | 2023/10/24 | Vitex agnus-castus | |
427213 | Active | 2023/11/01 | Vitex agnus-castus | ||
488266 | Active | 2025/05/09 | Vitex agnus-castus | ||
462678 | Active | 2024/09/24 | Vitex agnus-castus |