Nisoldipine
- Generic Name
- Nisoldipine
- Brand Names
- Sular
- Drug Type
- Small Molecule
- Chemical Formula
- C20H24N2O6
- CAS Number
- 63675-72-9
- Unique Ingredient Identifier
- 4I8HAB65SZ
Overview
Nisoldipine is a 1,4-dihydropyridine calcium channel blocker. It acts primarily on vascular smooth muscle cells by stabilizing voltage-gated L-type calcium channels in their inactive conformation. By inhibiting the influx of calcium in smooth muscle cells, nisoldipine prevents calcium-dependent smooth muscle contraction and subsequent vasoconstriction. Nisoldipine may be used in alone or in combination with other agents in the management of hypertension.
Background
Nisoldipine is a 1,4-dihydropyridine calcium channel blocker. It acts primarily on vascular smooth muscle cells by stabilizing voltage-gated L-type calcium channels in their inactive conformation. By inhibiting the influx of calcium in smooth muscle cells, nisoldipine prevents calcium-dependent smooth muscle contraction and subsequent vasoconstriction. Nisoldipine may be used in alone or in combination with other agents in the management of hypertension.
Indication
For the treatment of hypertension. It may be used alone or in combination with other antihypertensive agents.
Associated Conditions
- Hypertension
Clinical Trials
FDA Approved Products
Singapore Approved Products
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