Escitalopram

Generic Name
Escitalopram
Brand Names
Cipralex, Lexapro
Drug Type
Small Molecule
Chemical Formula
C20H21FN2O
CAS Number
128196-01-0
Unique Ingredient Identifier
4O4S742ANY
Background

Escitalopram is a selective serotonin re-uptake inhibitor (SSRI) and the S-enantiomer of racemic citalopram. It is used to restore serotonergic function in the treatment of depression and anxiety. Escitalopram is approximately 150 times more potent than citalopram’s R-enantiomer and is responsible for the vast majority of citalopram’s clinical activity, with...

Indication

Escitalopram is indicated for the acute and maintenance treatment of major depressive disorder (MDD) in adults and pediatric patients 12 years old and older and for the acute treatment of generalized anxiety disorder (GAD) in adults and pediatric patients 7 years old and older. It is additionally indicated for symptomatic relief of obsessive-compulsive disor...

Associated Conditions
Anxiety, Generalized Anxiety Disorder, Major Depressive Disorder (MDD), Obsessive Compulsive Disorder (OCD)
Associated Therapies
-

Safety and Effectiveness of S-adenosyl-l-methionine (SAMe) for the Treatment of Major Depression

First Posted Date
2005-01-11
Last Posted Date
2017-04-04
Lead Sponsor
Maurizio Fava, MD
Target Recruit Count
199
Registration Number
NCT00101452
Locations
🇺🇸

Butler Hospital, Providence, Rhode Island, United States

🇺🇸

Massachusetts General Hospital, Boston, Massachusetts, United States

Lexapro and Pramipexole and to Treat Major Depression

Phase 2
Completed
Conditions
Interventions
First Posted Date
2004-06-30
Last Posted Date
2013-01-28
Lead Sponsor
National Institute of Mental Health (NIMH)
Target Recruit Count
39
Registration Number
NCT00086307
Locations
🇺🇸

National Institutes of Health Clinical Center, 9000 Rockville Pike, Bethesda, Maryland, United States

Treatment of Adolescent Suicide Attempters (TASA)

Phase 2
Completed
Conditions
First Posted Date
2004-03-26
Last Posted Date
2020-06-22
Lead Sponsor
New York State Psychiatric Institute
Target Recruit Count
120
Registration Number
NCT00080158
Locations
🇺🇸

Johns Hopkins University, Baltimore, Maryland, United States

🇺🇸

Columbia University at the New York State Psychiatric Institute, New York, New York, United States

🇺🇸

New York University Child Study Center, New York, New York, United States

and more 3 locations

Treatment of Depression in Adults

First Posted Date
2003-12-03
Last Posted Date
2012-01-11
Lead Sponsor
University of Pittsburgh
Target Recruit Count
290
Registration Number
NCT00073697
Locations
🇺🇸

Western Psychiatric Institute and Clinic - Depression Prevention Program, Pittsburgh, Pennsylvania, United States

🇮🇹

The University of Pisa, Pisa, Italy

Duloxetine Compared to Escitalopram and Placebo in the Treatment of Patients With Depression

Phase 3
Completed
Conditions
First Posted Date
2003-11-21
Last Posted Date
2007-07-31
Lead Sponsor
Eli Lilly and Company
Target Recruit Count
675
Registration Number
NCT00073411
Locations
🇺🇸

For additional information regarding investigative sites for this trial, contact 1-877-CTLILLY (1-877-285-4559, 1-317-615-4559) Mon - Fri from 9 AM to 5 PM Eastern Time (UTC/GMT - 5 hours, EST) or speak with your personal physician., Cincinnati, Ohio, United States

Preventing Post-Stroke Depression

First Posted Date
2003-10-30
Last Posted Date
2017-09-05
Lead Sponsor
Robert G. Robinson
Target Recruit Count
201
Registration Number
NCT00071643
Locations
🇺🇸

University of Iowa Hospitals and Clinics, Iowa City, Iowa, United States

🇺🇸

Burke Rehabilitation Hospital, White Plains, New York, United States

🇺🇸

University of Chicago, Chicago, Illinois, United States

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