Ketamine
- Generic Name
- Ketamine
- Brand Names
- Ketalar
- Drug Type
- Small Molecule
- Chemical Formula
- C13H16ClNO
- CAS Number
- 6740-88-1
- Unique Ingredient Identifier
- 690G0D6V8H
- Background
Ketamine is an NMDA receptor antagonist with a potent anesthetic effect. It was developed in 1963 as a replacement for phencyclidine (PCP) by Calvin Stevens at Parke Davis Laboratories. It started being used for veterinary purposes in Belgium and in 1964 was proven that compared to PCP, it produced minor hallucinogenic effects and shorter psychotomimetic eff...
- Indication
Ketamine is indicated as an anesthetic agent for recommended diagnostic and surgical procedures. If skeletal muscle relaxation is needed, it should be combined with a muscle relaxant. If the surgical procedure involves visceral pain, it should be supplemented with an agent that obtunds visceral pain. Ketamine can be used for induction of anesthesia prior oth...
- Associated Conditions
- -
- Associated Therapies
- General Anesthesia, Induction and Maintenance of General Anesthesia
Comparison Between Ketamine Intrathecal and iv Dexamethasone for Post Cesarean Analgesia
- Conditions
- Interventions
- First Posted Date
- 2024-05-10
- Last Posted Date
- 2024-05-10
- Lead Sponsor
- Assiut University
- Target Recruit Count
- 90
- Registration Number
- NCT06408974
Psilocybin Vs Ketamine for Alcohol Use Disorder
- Conditions
- Interventions
- First Posted Date
- 2024-05-08
- Last Posted Date
- 2024-10-26
- Lead Sponsor
- University of Iowa
- Target Recruit Count
- 80
- Registration Number
- NCT06405607
Ketamine-assisted Psychotherapy for Adolescent PTSD (KAP)
- Conditions
- Interventions
- First Posted Date
- 2024-04-22
- Last Posted Date
- 2024-11-06
- Lead Sponsor
- University of Wisconsin, Madison
- Target Recruit Count
- 5
- Registration Number
- NCT06378528
- Locations
- 🇺🇸
University of Wisconsin, Madison, Wisconsin, United States
Nebulized Ketamine to Nebulized Fentanyl for Treating Acute Painful Conditions in the ED
- First Posted Date
- 2024-04-15
- Last Posted Date
- 2024-06-18
- Lead Sponsor
- Antonios Likourezos
- Target Recruit Count
- 150
- Registration Number
- NCT06364540
- Locations
- 🇺🇸
Maimonides Medical Center, Brooklyn, New York, United States
Stellate Ganglion Block Combined With Dexmedetomidine or Subanesthetic Ketamine Infusion for Treatment of Neurostorm.
- Conditions
- Interventions
- First Posted Date
- 2024-04-09
- Last Posted Date
- 2024-04-10
- Lead Sponsor
- Zagazig University
- Target Recruit Count
- 205
- Registration Number
- NCT06354673
- Locations
- 🇪🇬
Zagazig university, Zagazig, Egypt
Characterization of the Temporal Profile of the Anti-nociceptive Effect of Ketamine Bolus Measured With ANI
- First Posted Date
- 2024-04-03
- Last Posted Date
- 2024-08-22
- Lead Sponsor
- Pontificia Universidad Catolica de Chile
- Target Recruit Count
- 20
- Registration Number
- NCT06344858
- Locations
- 🇨🇱
Pontificia Universidad Catolica de Chile, Santiago, Metropolitana, Chile
Dexmedetomidine and Ketamine as an Adjuvant in External Oblique Intercostal Plane Block for Post Thoracotomy Pain
- Conditions
- Interventions
- First Posted Date
- 2024-03-26
- Last Posted Date
- 2024-03-27
- Lead Sponsor
- Tanta University
- Target Recruit Count
- 40
- Registration Number
- NCT06331182
- Locations
- 🇪🇬
Tanta University, Tanta, ElGharbia, Egypt
Propofol-Enhanced Assessment of Ketamine for Chronic Pain and Depression
- First Posted Date
- 2024-03-19
- Last Posted Date
- 2024-12-04
- Lead Sponsor
- Stanford University
- Target Recruit Count
- 40
- Registration Number
- NCT06317636
- Locations
- 🇺🇸
Stanford University, Stanford, California, United States
The Effect of Preprocedural Subanesthetic Ketamine on Pain and Anxiety
- Conditions
- Interventions
- First Posted Date
- 2024-03-15
- Last Posted Date
- 2024-03-15
- Target Recruit Count
- 60
- Registration Number
- NCT06310850
- Locations
- 🇹🇷
Ankara Atatürk Sanatorium Training and Research Hospital, Ankara, Keçiören, Turkey
Infusion Treatments of Chronic Peripheral Neuropathic Pain
- Conditions
- First Posted Date
- 2024-03-07
- Last Posted Date
- 2024-03-07
- Lead Sponsor
- Hacettepe University
- Target Recruit Count
- 102
- Registration Number
- NCT06297915
- Locations
- 🇹🇷
Hacettepe University, Ankara, Cankaya, Turkey
Drug Development Updates
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