Ketamine

Generic Name
Ketamine
Brand Names
Ketalar
Drug Type
Small Molecule
Chemical Formula
C13H16ClNO
CAS Number
6740-88-1
Unique Ingredient Identifier
690G0D6V8H
Background

Ketamine is an NMDA receptor antagonist with a potent anesthetic effect. It was developed in 1963 as a replacement for phencyclidine (PCP) by Calvin Stevens at Parke Davis Laboratories. It started being used for veterinary purposes in Belgium and in 1964 was proven that compared to PCP, it produced minor hallucinogenic effects and shorter psychotomimetic eff...

Indication

Ketamine is indicated as an anesthetic agent for recommended diagnostic and surgical procedures. If skeletal muscle relaxation is needed, it should be combined with a muscle relaxant. If the surgical procedure involves visceral pain, it should be supplemented with an agent that obtunds visceral pain. Ketamine can be used for induction of anesthesia prior oth...

Associated Conditions
-
Associated Therapies
General Anesthesia, Induction and Maintenance of General Anesthesia

Ketamine for OUD and Suicidal Ideation in the ED

First Posted Date
2023-11-01
Last Posted Date
2024-05-16
Lead Sponsor
Brigham and Women's Hospital
Target Recruit Count
50
Registration Number
NCT06111339
Locations
🇺🇸

Brigham and Women's Hospital, Boston, Massachusetts, United States

Ketamine-midazolam as a Sedative Agent in Endoscopic Retrograde Cholangiopancreatography.

First Posted Date
2023-11-01
Last Posted Date
2024-03-15
Lead Sponsor
National University of Malaysia
Target Recruit Count
90
Registration Number
NCT06111872
Locations
🇲🇾

Hospital Canselor Tuanku Muhriz UKM, Cheras, Kuala Lumpur, Malaysia

Feasibility and Safety of Ketamine for Suicidal Patients in the Emergency Department

Phase 1
Recruiting
Conditions
Interventions
First Posted Date
2023-10-17
Last Posted Date
2024-04-25
Lead Sponsor
Lindsay Maguire, MD
Target Recruit Count
50
Registration Number
NCT06085937
Locations
🇺🇸

University of Kansas Strawberry Hill Campus, Kansas City, Kansas, United States

🇺🇸

University of Kansas Medical Center Emergency Department, Kansas City, Kansas, United States

Prevention of Shivering Associated With Spinal Anesthesia

First Posted Date
2023-10-13
Last Posted Date
2023-10-13
Lead Sponsor
Assiut University
Target Recruit Count
90
Registration Number
NCT06082076

Dexmedetomidine Versus Ketamine Versus Magnesium Sulfate for the Prevention of Emergence Agitation Following Sevoflurane Induced Anesthesia in Cardiac Catheterization in Pediatrics

First Posted Date
2023-10-11
Last Posted Date
2023-10-11
Lead Sponsor
Cairo University
Target Recruit Count
100
Registration Number
NCT06077539
Locations
🇪🇬

Amany Hassan Saleh, Giza, Egypt

Ketamine-assisted Therapy for Advanced GI Cancer

First Posted Date
2023-10-11
Last Posted Date
2024-11-18
Lead Sponsor
Brian Anderson, MD
Target Recruit Count
12
Registration Number
NCT06077487
Locations
🇺🇸

University of California, San Francisco, San Francisco, California, United States

RIVER At Home Ketamine Protocols

First Posted Date
2023-10-06
Last Posted Date
2024-11-26
Lead Sponsor
RIVER Foundation
Target Recruit Count
50000
Registration Number
NCT06070766
Locations
🇺🇸

RIVER Telehealth, Helena, Montana, United States

🇺🇸

RIVER Foundation, Bigfork, Montana, United States

Ketamine for MS Fatigue

Early Phase 1
Recruiting
Conditions
Interventions
First Posted Date
2023-10-03
Last Posted Date
2024-06-06
Lead Sponsor
Alta Bates Summit Medical Center
Target Recruit Count
20
Registration Number
NCT06064162
Locations
🇺🇸

Alta Bates Summit Medical Center, Berkeley, California, United States

Impact of Ketamine on Depressive Symptoms in Patients Undergoing Lumbo-peritoneal Shunt Insertion

Phase 4
Completed
Conditions
Interventions
First Posted Date
2023-09-29
Last Posted Date
2024-12-05
Lead Sponsor
Benha University
Target Recruit Count
60
Registration Number
NCT06060210
Locations
🇪🇬

Banha faculity of medicine, Banha, Elqalyoubea, Egypt

The Perinatal Synergistic Multi-component Intervention to alLeviate dEpressive Symptoms. A Case Series

First Posted Date
2023-09-21
Last Posted Date
2024-06-24
Lead Sponsor
Washington University School of Medicine
Target Recruit Count
25
Registration Number
NCT06048263
Locations
🇺🇸

Barnes-Jewish Hospital, Saint Louis, Missouri, United States

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