Ketamine
- Generic Name
- Ketamine
- Brand Names
- Ketalar
- Drug Type
- Small Molecule
- Chemical Formula
- C13H16ClNO
- CAS Number
- 6740-88-1
- Unique Ingredient Identifier
- 690G0D6V8H
- Background
Ketamine is an NMDA receptor antagonist with a potent anesthetic effect. It was developed in 1963 as a replacement for phencyclidine (PCP) by Calvin Stevens at Parke Davis Laboratories. It started being used for veterinary purposes in Belgium and in 1964 was proven that compared to PCP, it produced minor hallucinogenic effects and shorter psychotomimetic eff...
- Indication
Ketamine is indicated as an anesthetic agent for recommended diagnostic and surgical procedures. If skeletal muscle relaxation is needed, it should be combined with a muscle relaxant. If the surgical procedure involves visceral pain, it should be supplemented with an agent that obtunds visceral pain. Ketamine can be used for induction of anesthesia prior oth...
- Associated Conditions
- -
- Associated Therapies
- General Anesthesia, Induction and Maintenance of General Anesthesia
Synaptic Imaging and Network Activity in Treatment Resistant Depression
- First Posted Date
- 2023-05-23
- Last Posted Date
- 2024-11-18
- Lead Sponsor
- King's College London
- Target Recruit Count
- 56
- Registration Number
- NCT05870501
- Locations
- 🇬🇧
The Institute of Psychiatry, Psychology & Neuroscience, King's College London, London, United Kingdom
Effect of Intravenous Ketamine Infusion for Hemodynamic Stability in Patients Undergoing Caesarean Delivery.
- First Posted Date
- 2023-05-18
- Last Posted Date
- 2023-05-22
- Lead Sponsor
- Azhar University
- Target Recruit Count
- 126
- Registration Number
- NCT05865080
- Locations
- 🇪🇬
Faculty of medicine -Al-Azhar university, Cairo, Egypt
(2R,6R)-Hydroxynorketamine for the Treatment of Neuropathic Pain
- Conditions
- Interventions
- First Posted Date
- 2023-05-18
- Last Posted Date
- 2024-10-01
- Lead Sponsor
- Rush University Medical Center
- Target Recruit Count
- 25
- Registration Number
- NCT05864053
- Locations
- 🇺🇸
Rush University Medical Center, Chicago, Illinois, United States
Dexmedetomidine, Ketamine and Magnesium Sulphate in Caudal Block for Hypospadias Repair
- Conditions
- Interventions
- First Posted Date
- 2023-05-01
- Last Posted Date
- 2023-06-13
- Lead Sponsor
- Kafrelsheikh University
- Target Recruit Count
- 75
- Registration Number
- NCT05837000
- Locations
- 🇪🇬
Karelsheikh University Hospital, Kafr Ash Shaykh, Karelsheikh, Egypt
Effect of Ketamine Infusion on BIS Values
- First Posted Date
- 2023-04-05
- Last Posted Date
- 2023-10-19
- Lead Sponsor
- University of Padova
- Target Recruit Count
- 40
- Registration Number
- NCT05799729
- Locations
- 🇮🇹
Treviso Regional Hospital, Treviso, TV, Italy
The Impact of AMPA Receptor Blockade on Ketamine's Anti-Suicidal Effects
- Conditions
- Interventions
- First Posted Date
- 2023-03-27
- Last Posted Date
- 2023-09-13
- Lead Sponsor
- Yale University
- Target Recruit Count
- 30
- Registration Number
- NCT05786066
- Locations
- 🇺🇸
VA Connecticut Healthcare System, West Haven, Connecticut, United States
Combined Ketamine and Midazolam for Generalized Convulsive Status Epilepticus
- Conditions
- Interventions
- First Posted Date
- 2023-03-22
- Last Posted Date
- 2024-10-29
- Lead Sponsor
- Sohag University
- Target Recruit Count
- 144
- Registration Number
- NCT05779657
- Locations
- 🇪🇬
Sohag University Hospital, Sohag, Egypt
Dual Anti-glutamate Therapy in Super-refractory Status Epilepticus After Cardiac Arrest
- Conditions
- Interventions
- First Posted Date
- 2023-03-06
- Last Posted Date
- 2024-12-19
- Lead Sponsor
- University of Milano Bicocca
- Target Recruit Count
- 80
- Registration Number
- NCT05756621
- Locations
- 🇮🇹
Ospedale Santa Chiara Trento, Trento, TN, Italy
🇮🇹Ospedale G. Brotzu, Cagliari, CA, Italy
🇮🇹Azienda Ospedaliero-Universitaria di Modena, Modena, MO, Italy
A Comparative Study Between Intrathecal Dexmedetomidine VS Ketamine With Intrathecal Bupivacaine in Orthopedic Lower Limb Surgeries.
- Conditions
- Interventions
- First Posted Date
- 2023-03-02
- Last Posted Date
- 2023-03-02
- Lead Sponsor
- Sohag University
- Target Recruit Count
- 100
- Registration Number
- NCT05751304
- Locations
- 🇪🇬
Sohag University Hospital, Sohag, Egypt
Effects of Subanesthetic Dose of Ketamine Given on Postoperative Mood in Patients Undergoing Fractional Curettage
- Conditions
- Interventions
- First Posted Date
- 2023-03-02
- Last Posted Date
- 2023-12-06
- Lead Sponsor
- Istanbul Training and Research Hospital
- Target Recruit Count
- 140
- Registration Number
- NCT05752110
- Locations
- 🇹🇷
Istanbul Training and Research Hospital, Istanbul, Fatih, Turkey
🇹🇷IstanbulTRH, Istanbul, Turkey
Drug Development Updates
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