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Lormetazepam is a benzodiazepine indicated in the treatment of anxiety and the induction of anesthesia.
Lormetazepam is a benzodiazepine indicated in the treatment of anxiety and the induction of anesthesia.
Lormetazepam, as a benzodiazepine, binds to the regulatory site between the α and γ subunits of γ-aminobutryic acid (GABA) A receptors with γ2 and α1, α2, α3, or α5 subunits . This facilitates the opening of the chloride channel allowing chloride ions to flow into the neuron resulting in hyperpolarization. Hyperpolarized neurons require greater simulation to reach their action potential threshold. The general inhibitory effect on neuronal depolarization produces the effects of lormetazepam.
For the treatment of short-term insomnia
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