MedPath

Codeine

Generic Name
Codeine
Brand Names
Ascomp, Cheratussin, Cheratussin Dac, Codar Ar, Codar D, Codar Gf, Codeine Contin, Covan, Damylin With Codeine, Fioricet With Codeine, Histex Ac, Linctus Codeine Blanc, M-clear Wc, M-end PE, Mar-cof BP, Mar-cof Cg, Mersyndol, Ninjacof Xg, Pseudodine C, Robaxacet-8, Robaxisal, Triacin-C, Trianal C, Triatec, Triatec-30, Triatec-8, Tusnel C, Tuxarin, Tuzistra, Tylenol With Codeine
Drug Type
Small Molecule
Chemical Formula
C18H21NO3
CAS Number
76-57-3
Unique Ingredient Identifier
UX6OWY2V7J

Overview

The relief of pain (analgesia) is a primary goal for enhancing the quality of life of patients and for increasing the ability of patients to engage in day to day activities. Codeine, an opioid analgesic, was originally approved in the US in 1950 and is a drug used to decrease pain by increasing the threshold for pain without impairing consciousness or altering other sensory functions. Opiates such as codeine are derived from the poppy plant, Papaver somniferum (Papaveraceae). Codeine is utilized as a central analgesic, sedative, hypnotic, antinociceptive, and antiperistaltic agent, and is also recommended in certain diseases with incessant coughing.

Background

The relief of pain (analgesia) is a primary goal for enhancing the quality of life of patients and for increasing the ability of patients to engage in day to day activities. Codeine, an opioid analgesic, was originally approved in the US in 1950 and is a drug used to decrease pain by increasing the threshold for pain without impairing consciousness or altering other sensory functions. Opiates such as codeine are derived from the poppy plant, Papaver somniferum (Papaveraceae). Codeine is utilized as a central analgesic, sedative, hypnotic, antinociceptive, and antiperistaltic agent, and is also recommended in certain diseases with incessant coughing.

Indication

Codeine sulfate is a form of this drug that is commonly used. It is available in tablet form and indicated for the relief of mild to moderately severe pain, where the use of an opioid analgesic is appropriate . The solution form is used by itself or combined in a syrup with other drugs and is used as a cough suppressant in adults aged 18 and above , .

Associated Conditions

  • Common Cold
  • Cough
  • Flu caused by Influenza
  • Mild pain
  • Pain
  • Severe Pain
  • Dry cough
  • Moderate Pain
  • Upper respiratory symptoms

FDA Approved Products

Butalbital, Acetaminophen, Caffeine, and Codeine Phosphate
Manufacturer:LGM Pharma Solutions, LLC
Route:ORAL
Strength:30 mg in 1 1
Approved: 2020/08/12
NDC:79739-7028
ACETAMINOPHEN AND CODEINE PHOSPHATE
Manufacturer:Eywa Pharma Inc
Route:ORAL
Strength:30 mg in 1 1
Approved: 2021/05/20
NDC:71930-055
ACETAMINOPHEN AND CODEINE PHOSPHATE
Manufacturer:Bryant Ranch Prepack
Route:ORAL
Strength:15 mg in 1 1
Approved: 2023/05/19
NDC:63629-1185
ACETAMINOPHEN AND CODEINE PHOSPHATE
Manufacturer:SpecGx LLC
Route:ORAL
Strength:60 mg in 1 1
Approved: 2023/12/28
NDC:0406-0485
Acetaminophen and Codeine Phosphate
Manufacturer:A-S Medication Solutions
Route:ORAL
Strength:12 mg in 5 mL
Approved: 2018/08/13
NDC:50090-0215

Singapore Approved Products

BEACTAFED CO SYRUP
Manufacturer:BEACONS PHARMACEUTICALS PTE LTD
Form:SYRUP
Strength:10 mg/5 ml
Online:Yes
Approved: 1989/05/30
Approval:SIN03140P
COLINCTUS 10 MIXTURE 10 mg/5 ml
Manufacturer:ICM PHARMA PTE. LTD.
Form:ELIXIR
Strength:10 mg/5 ml
Online:Yes
Approved: 1989/06/22
Approval:SIN03413P
COPHADYL COUGH LINCTUS
Manufacturer:ICM PHARMA PTE. LTD.
Form:ELIXIR
Strength:9 mg/5 ml
Online:Yes
Approved: 1996/12/14
Approval:SIN09071P
L.T.R. COUGH LINCTUS 10 mg/5 ml
Manufacturer:BEACONS PHARMACEUTICALS PTE LTD
Form:ELIXIR
Strength:10 mg/5 ml
Online:Yes
Approved: 1989/08/05
Approval:SIN03699P
FEDAC COMPOUND LINCTUS
Manufacturer:ICM PHARMA PTE. LTD.
Form:ELIXIR
Strength:10 mg/5 ml
Online:Yes
Approved: 1989/06/01
Approval:SIN03195P

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