MedPath

Codeine

Generic Name
Codeine
Brand Names
Ascomp, Cheratussin, Cheratussin Dac, Codar Ar, Codar D, Codar Gf, Codeine Contin, Covan, Damylin With Codeine, Fioricet With Codeine, Histex Ac, Linctus Codeine Blanc, M-clear Wc, M-end PE, Mar-cof BP, Mar-cof Cg, Mersyndol, Ninjacof Xg, Pseudodine C, Robaxacet-8, Robaxisal, Triacin-C, Trianal C, Triatec, Triatec-30, Triatec-8, Tusnel C, Tuxarin, Tuzistra, Tylenol With Codeine
Drug Type
Small Molecule
Chemical Formula
C18H21NO3
CAS Number
76-57-3
Unique Ingredient Identifier
UX6OWY2V7J

Overview

The relief of pain (analgesia) is a primary goal for enhancing the quality of life of patients and for increasing the ability of patients to engage in day to day activities. Codeine, an opioid analgesic, was originally approved in the US in 1950 and is a drug used to decrease pain by increasing the threshold for pain without impairing consciousness or altering other sensory functions. Opiates such as codeine are derived from the poppy plant, Papaver somniferum (Papaveraceae). Codeine is utilized as a central analgesic, sedative, hypnotic, antinociceptive, and antiperistaltic agent, and is also recommended in certain diseases with incessant coughing.

Background

The relief of pain (analgesia) is a primary goal for enhancing the quality of life of patients and for increasing the ability of patients to engage in day to day activities. Codeine, an opioid analgesic, was originally approved in the US in 1950 and is a drug used to decrease pain by increasing the threshold for pain without impairing consciousness or altering other sensory functions. Opiates such as codeine are derived from the poppy plant, Papaver somniferum (Papaveraceae). Codeine is utilized as a central analgesic, sedative, hypnotic, antinociceptive, and antiperistaltic agent, and is also recommended in certain diseases with incessant coughing.

Indication

Codeine sulfate is a form of this drug that is commonly used. It is available in tablet form and indicated for the relief of mild to moderately severe pain, where the use of an opioid analgesic is appropriate . The solution form is used by itself or combined in a syrup with other drugs and is used as a cough suppressant in adults aged 18 and above , .

Associated Conditions

  • Common Cold
  • Cough
  • Flu caused by Influenza
  • Mild pain
  • Pain
  • Severe Pain
  • Dry cough
  • Moderate Pain
  • Upper respiratory symptoms

FDA Approved Products

ACETAMINOPHEN AND CODEINE PHOSPHATE
Manufacturer:Bryant Ranch Prepack
Route:ORAL
Strength:30 mg in 1 1
Approved: 2021/05/20
NDC:63629-1188
Promethazine Hydrochloride and Codeine Phosphate
Manufacturer:QUAGEN PHARMACEUTICALS LLC
Route:ORAL
Strength:10 mg in 5 mL
Approved: 2023/02/15
NDC:70752-139
Codeine sulfate
Manufacturer:Hikma Pharmaceuticals USA Inc.
Route:ORAL
Strength:30 mg in 1 1
Approved: 2021/03/15
NDC:0054-0244
Acetaminophen and Codeine Phosphate
Manufacturer:Redpharm Drug, Inc
Route:ORAL
Strength:12 mg in 5 mL
Approved: 2023/02/10
NDC:67296-0525
Acetaminophen and Codeine Phosphate
Manufacturer:Genus Lifesciences Inc.
Route:ORAL
Strength:12 mg in 5 mL
Approved: 2023/08/16
NDC:64950-374

Singapore Approved Products

SUNSEDYL COUGH LINCTUS
Manufacturer:SUNWARD PHARMACEUTICAL PRIVATE LIMITED
Form:ELIXIR
Strength:9 mg/5 ml
Online:Yes
Approved: 1989/06/26
Approval:SIN03490P
SUNSEDYL FORTE COUGH LINCTUS
Manufacturer:SUNWARD PHARMACEUTICAL PRIVATE LIMITED
Form:ELIXIR
Strength:10.0 mg/5 ml
Online:Yes
Approved: 1994/06/21
Approval:SIN07750P
UNIDRYL CD EXPECTORANT
Manufacturer:SUNWARD PHARMACEUTICAL PRIVATE LIMITED
Form:SYRUP
Strength:5mg/5ml
Online:Yes
Approved: 1989/05/22
Approval:SIN02917P
PHENEXPECT CD SYRUP
Manufacturer:ICM PHARMA PTE. LTD.
Form:SYRUP
Strength:5.7 mg/5 ml
Online:Yes
Approved: 1991/12/03
Approval:SIN06702P
PARACETAMOL CODEINE TABLETS
Manufacturer:SUNWARD PHARMACEUTICAL PRIVATE LIMITED
Form:TABLET
Strength:8 mg
Online:Yes
Approved: 1991/07/02
Approval:SIN06330P

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