MedPath

Codeine

Generic Name
Codeine
Brand Names
Ascomp, Cheratussin, Cheratussin Dac, Codar Ar, Codar D, Codar Gf, Codeine Contin, Covan, Damylin With Codeine, Fioricet With Codeine, Histex Ac, Linctus Codeine Blanc, M-clear Wc, M-end PE, Mar-cof BP, Mar-cof Cg, Mersyndol, Ninjacof Xg, Pseudodine C, Robaxacet-8, Robaxisal, Triacin-C, Trianal C, Triatec, Triatec-30, Triatec-8, Tusnel C, Tuxarin, Tuzistra, Tylenol With Codeine
Drug Type
Small Molecule
Chemical Formula
C18H21NO3
CAS Number
76-57-3
Unique Ingredient Identifier
UX6OWY2V7J

Overview

The relief of pain (analgesia) is a primary goal for enhancing the quality of life of patients and for increasing the ability of patients to engage in day to day activities. Codeine, an opioid analgesic, was originally approved in the US in 1950 and is a drug used to decrease pain by increasing the threshold for pain without impairing consciousness or altering other sensory functions. Opiates such as codeine are derived from the poppy plant, Papaver somniferum (Papaveraceae). Codeine is utilized as a central analgesic, sedative, hypnotic, antinociceptive, and antiperistaltic agent, and is also recommended in certain diseases with incessant coughing.

Background

The relief of pain (analgesia) is a primary goal for enhancing the quality of life of patients and for increasing the ability of patients to engage in day to day activities. Codeine, an opioid analgesic, was originally approved in the US in 1950 and is a drug used to decrease pain by increasing the threshold for pain without impairing consciousness or altering other sensory functions. Opiates such as codeine are derived from the poppy plant, Papaver somniferum (Papaveraceae). Codeine is utilized as a central analgesic, sedative, hypnotic, antinociceptive, and antiperistaltic agent, and is also recommended in certain diseases with incessant coughing.

Indication

Codeine sulfate is a form of this drug that is commonly used. It is available in tablet form and indicated for the relief of mild to moderately severe pain, where the use of an opioid analgesic is appropriate . The solution form is used by itself or combined in a syrup with other drugs and is used as a cough suppressant in adults aged 18 and above , .

Associated Conditions

  • Common Cold
  • Cough
  • Flu caused by Influenza
  • Mild pain
  • Pain
  • Severe Pain
  • Dry cough
  • Moderate Pain
  • Upper respiratory symptoms

FDA Approved Products

ACETAMINOPHEN AND CODEINE PHOSPHATE
Manufacturer:SpecGx LLC
Route:ORAL
Strength:15 mg in 1 1
Approved: 2023/12/28
NDC:0406-0483
ACETAMINOPHEN AND CODEINE
Manufacturer:Direct_Rx
Route:ORAL
Strength:30 mg in 1 1
Approved: 2023/04/25
NDC:61919-484
ACETAMINOPHEN AND CODEINE PHOSPHATE
Manufacturer:NuCare Pharmaceuticals,Inc.
Route:ORAL
Strength:60 mg in 1 1
Approved: 2022/07/19
NDC:68071-2800
Acetaminophen and Codeine
Manufacturer:Proficient Rx LP
Route:ORAL
Strength:30 mg in 1 1
Approved: 2021/01/01
NDC:63187-491
Tuxarin
Manufacturer:Mainpointe Pharmaceuticals
Route:ORAL
Strength:54.3 mg in 1 1
Approved: 2023/12/31
NDC:71269-040

Singapore Approved Products

CHLORSEDYL LINCTUS
Manufacturer:BEACONS PHARMACEUTICALS PTE LTD
Form:ELIXIR
Strength:9 mg/5 ml
Online:Yes
Approved: 1989/05/22
Approval:SIN02933P
PACOFEN TABLETS
Manufacturer:BEACONS PHARMACEUTICALS PTE. LTD., SRI KRISHNA PHARMACEUTICALS LTD [Intermediate manufacturer]
Form:TABLET
Strength:8 mg
Online:Yes
Approved: 1991/05/07
Approval:SIN06271P
DHASEDYL SYRUP
Manufacturer:ICM PHARMA PTE. LTD.
Form:SYRUP
Strength:9 mg/5 ml
Online:Yes
Approved: 1992/04/13
Approval:SIN06928P
COPHADYL-E COUGH LINCTUS
Manufacturer:ICM PHARMA PTE. LTD.
Form:ELIXIR
Strength:9 mg/5 ml
Online:Yes
Approved: 1996/12/28
Approval:SIN09104P
PANACO TABLETS
Manufacturer:BEACONS PHARMACEUTICALS PTE LTD, BEACONS PHARMACEUTICALS PTE. LTD.
Form:TABLET
Strength:9 mg
Online:Yes
Approved: 1991/02/19
Approval:SIN05462P

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