Sparfloxacin
- Generic Name
- Sparfloxacin
- Drug Type
- Small Molecule
- Chemical Formula
- C19H22F2N4O3
- CAS Number
- 110871-86-8
- Unique Ingredient Identifier
- Q90AGA787L
Overview
Sparfloxacin is a fluoroquinolone antibiotic indicated for bacterial infections. Sparfloxacin exerts its antibacterial activity by inhibiting DNA gyrase, a bacterial topoisomerase. DNA gyrase is an essential enzyme which controls DNA topology and assists in DNA replication, repair, deactivation, and transcription.
Background
Sparfloxacin is a fluoroquinolone antibiotic indicated for bacterial infections. Sparfloxacin exerts its antibacterial activity by inhibiting DNA gyrase, a bacterial topoisomerase. DNA gyrase is an essential enzyme which controls DNA topology and assists in DNA replication, repair, deactivation, and transcription.
Indication
For the treatment of adults with the following infections caused by susceptible strains microorganisms: community-acquired pneumonia (caused by Chlamydia pneumoniae, Haemophilus influenzae, Haemophilus parainfluenzae, Moraxella catarrhalis, Mycoplasma pneumoniae, or Streptococcus pneumoniae) and acute bacterial exacerbations of chronic bronchitis (caused by Chlamydia pneumoniae, Enterobacter cloacae, Haemophilus influenzae, Haemophilus parainfluenzae, Klebsiella pneumoniae, Moraxella catarrhalis, Staphylococcus aureus, or Streptococcus pneumoniae).
Associated Conditions
- Acute Sinusitis
- Community Acquired Pneumonia (CAP)
- Exacerbation of COPD
- Susceptible infections
Clinical Trials
Title | Posted | Study ID | Phase | Status | Sponsor |
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No clinical trials found
No clinical trials found for this drug
FDA Approved Products
Product Name | Manufacturer | Route | Strength | Approved | NDC Code |
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No FDA products found
No FDA products found for this drug
EMA Approved Products
Medicine Name | EMA Number | Auth. Holder | Country | Drug Type | Status | Issued | Opinion | Revision |
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No EMA products found
No EMA products found for this drug
HSA Approved Products
Product Name | Manufacturer | Dosage Form | Strength | Approved | Approval No. |
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No HSA products found
No HSA products found for this drug
NMPA Approved Products
Product Name | Approval No. | Manufacturer | Dosage Form | Trade Name | Strength | Type | Status | Date | Import |
|---|---|---|---|---|---|---|---|---|---|
国药准字H10980233 | 胶囊剂 | 海正立特 | 0.1g | Chemical Drug | Approved | 2020/05/22 | Domestic | ||
国药准字H20093485 | 胶囊剂 | N/A | 0.1g | Chemical Drug | Approved | 2023/09/22 | Domestic | ||
国药准字H20103415 | 胶囊剂 | N/A | 0.1g | Chemical Drug | Approved | 2020/03/13 | Domestic | ||
国药准字H20113104 | 胶囊剂 | N/A | 0.1g | Chemical Drug | Approved | 2020/06/22 | Domestic | ||
国药准字H10980130 | 胶囊剂 | 森澳欣 | 0.1g | Chemical Drug | Approved | 2020/06/24 | Domestic | ||
国药准字H20093695 | 胶囊剂 | N/A | 0.1g | Chemical Drug | Approved | 2023/07/10 | Domestic | ||
国药准字H10980056 | 胶囊剂 | 巴沙 | 0.1g | Chemical Drug | Approved | 2019/12/02 | Domestic | ||
国药准字H20020453 | 片剂 | 力贝尔 | 0.1g(按C19H22F2N4O3计) | Chemical Drug | Approved | 2020/07/30 | Domestic | ||
国药准字H20051254 | 片剂 | 星特 | 0.1g(以司帕沙星计) | Chemical Drug | Approved | 2020/05/07 | Domestic | ||
国药准字H20065256 | 片剂 | N/A | 0.15g | Chemical Drug | Approved | 2020/08/26 | Domestic |
PPB Approved Products
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No PPB products found
No PPB products found for this drug
TGA Approved Products
Product Name | ARTG ID | Sponsor | Status | Reg. Date | Ingredient |
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No TGA products found
No TGA products found for this drug