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Ruplizumab is a humanized monoclonal antibody used as an immunosuppressive drug and is a component of Antova.
Ruplizumab is a humanized monoclonal antibody used as an immunosuppressive drug and is a component of Antova.
Ruplizumab is an anti-CD40L monoclonal antibody. The binding of CD40 to its ligand, CD40L, is a critical element in T cell activation. In systemic lupus erythematosus, CD40L is over-expressed on T cells, B cells, and monocytes.
Investigated for use/treatment in thrombocytopenia, systemic lupus erythematosus, transplant (rejection), blood (blood forming organ disorders, unspecified), and multiple sclerosis.
每项发明一条，涵盖美国、欧洲、PCT 与中国的同族专利。
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专利文献通常使用化学名或研发代号指代药物，而非通用名；且专利申请在提交约 18 个月后才公开，较新的药物可能尚未出现在这里。
