Lansoprazole

Generic Name
Lansoprazole
Brand Names
Prevacid, Prevpac
Drug Type
Small Molecule
Chemical Formula
C16H14F3N3O2S
CAS Number
103577-45-3
Unique Ingredient Identifier
0K5C5T2QPG
Background

Lansoprazole marketed under the brand Prevacid, is a proton pump inhibitor (PPI) and is structurally classified as a substituted benzimidazole. It reduces gastric acid secretion by targeting gastric H,K-ATPase pumps and is thus effective at promoting healing in ulcerative diseases, and treating gastroesophageal reflux disease (GERD) along with other patholog...

Indication

Lansoprazole is used to reduce gastric acid secretion and is approved for short term treatment of active gastric ulcers, active duodenal ulcers, erosive reflux oesophagitis, symptomatic gastroesophageal reflux disease, and non-steroidal anti-inflammatory drug (NSAID) induced gastric and duodenal ulcers. It may be used in the maintenance and healing of sever...

Associated Conditions
Duodenal Ulcer, Erosive Esophagitis, Helicobacter Pylori Infection, Symptomatic Gastroesophageal Reflux Disease (sGERD), Ulcer Healing, Zollinger-Ellison Syndrome, Active Duodenal ulcer, Develop NSAID-induced gastric ulcers, Hypersecretory conditions, Maintenance of healing Erosive esophagitis
Associated Therapies
-

Study to Evaluate the Efficacy and Safety of Ilaprazole 10 mg in Prevention NSAIDs Associated Peptic Ulcer

First Posted Date
2024-02-29
Last Posted Date
2024-02-29
Lead Sponsor
Il-Yang Pharm. Co., Ltd.
Target Recruit Count
416
Registration Number
NCT06284876
Locations
🇰🇷

Chung Ang University Hospital, Seoul, Korea, Republic of

Efficacy of Fexuprazan for Prevention or Control of Gastritis Symptoms in Patients on Treatment With Systemic Steroids

First Posted Date
2023-07-14
Last Posted Date
2023-07-14
Lead Sponsor
Yonsei University
Target Recruit Count
70
Registration Number
NCT05946135
Locations
🇰🇷

Severance Hospital, Seoul, Korea, Republic of

A "Screen and Treat" Helicobacter Pylori Eradication Trial in Adolescents in Three Regions of Chile

First Posted Date
2023-07-03
Last Posted Date
2024-12-20
Lead Sponsor
Miguel O'Ryan Gallardo
Target Recruit Count
500
Registration Number
NCT05926804
Locations
🇨🇱

Universidad de Chile, Santiago, Chile

🇨🇱

Universidad de Aysén, Coyhaique, Chile

🇨🇱

Universidad de la Frontera, Temuco, Chile

Recurrence Rate Comparison Between Esomeprazole and Lansoprazole in Eradicating Helicobacter Pylori Infection Among Children

First Posted Date
2023-05-17
Last Posted Date
2023-05-17
Lead Sponsor
Finni Kollins
Target Recruit Count
51
Registration Number
NCT05861687
Locations
🇮🇩

Universitas Sumatera Utara General Hospital, Medan, North Sumatera, Indonesia

🇮🇩

Haji Adam Malik General Hospital, Medan, North Sumatera, Indonesia

Effect of Kunamin in SARS-CoV-2 RT-PCR Positive Covid-19 Patients

First Posted Date
2022-06-14
Last Posted Date
2022-06-14
Lead Sponsor
RAAS Nutritionals, LLC
Target Recruit Count
71
Registration Number
NCT05417997
Locations
🇹🇷

Kayseri City Hospital, Kayseri, Kayseri Province, Turkey

A Study in Patients With Erosive Esophagitis to Investigate Safety, Tolerability, and Healing Rates After 4 Weeks Treatment of X842 or Lansoprazole and Symptom Pattern During Subsequent 4 Weeks Treatment With Lansoprazole

First Posted Date
2021-09-24
Last Posted Date
2023-11-01
Lead Sponsor
Cinclus Pharma AG
Target Recruit Count
248
Registration Number
NCT05055128
Locations
🇧🇬

DCC XIV Sofia, Sofia, Sofia-Grad, Bulgaria

🇧🇬

Medical Centre Asklepii, Dupnitsa, Bulgaria

🇧🇬

Medical Center Prolet EOOD, Ruse, Bulgaria

and more 35 locations

A Study to Evaluate the Safety, Tolerability and Pharmacokinetics/Pharmacodynamics of Oral Doses of H008

First Posted Date
2021-09-20
Last Posted Date
2023-12-15
Lead Sponsor
Jiangsu Carephar Pharmaceutical Co., Ltd.
Target Recruit Count
24
Registration Number
NCT05050188
Locations
🇺🇸

Syneos Health, Miami, Florida, United States

Treating People With Idiopathic Pulmonary Fibrosis With the Addition of Lansoprazole

First Posted Date
2021-07-16
Last Posted Date
2023-12-18
Lead Sponsor
Norfolk and Norwich University Hospitals NHS Foundation Trust
Target Recruit Count
298
Registration Number
NCT04965298
Locations
🇬🇧

Norfolk and Norwich University Hospitals NHS Foundation Trust, Norwich, Norfolk, United Kingdom

The Possible Efficacy and Safety of Lansoprazole Co-administration With Neoadjuvant Chemotherapy in Women With Breast Cancer

Phase 3
Completed
Conditions
Interventions
First Posted Date
2021-05-06
Last Posted Date
2022-11-15
Lead Sponsor
Tanta University
Target Recruit Count
66
Registration Number
NCT04874935
Locations
🇪🇬

Faculty of Pharmacy, Tanta, Egypt

Study to Evaluate the Pharmacokinetics, Pharmacodynamics, and Safety of Vonoprazan and Lansoprazole in Healthy Participants

Phase 1
Completed
Conditions
Interventions
First Posted Date
2021-01-28
Last Posted Date
2023-03-31
Lead Sponsor
Phathom Pharmaceuticals, Inc.
Target Recruit Count
44
Registration Number
NCT04729101
Locations
🇺🇸

Celerion, 2420 W Baseline Rd,, Tempe, Arizona, United States

© Copyright 2024. All Rights Reserved by MedPath