Lansoprazole marketed under the brand Prevacid, is a proton pump inhibitor (PPI) and is structurally classified as a substituted benzimidazole. It reduces gastric acid secretion by targeting gastric H,K-ATPase pumps and is thus effective at promoting healing in ulcerative diseases, and treating gastroesophageal reflux disease (GERD) along with other pathologies caused by excessive acid secretion.
Lansoprazole is used to reduce gastric acid secretion and is approved for short term treatment of active gastric ulcers, active duodenal ulcers, erosive reflux oesophagitis, symptomatic gastroesophageal reflux disease, and non-steroidal anti-inflammatory drug (NSAID) induced gastric and duodenal ulcers. It may be used in the maintenance and healing of several gastric conditions including duodenal ulcers, NSAID related gastric ulcers, and erosive esophagitis. Lansoprazole prevents recurrence of gastric ulcers in patients who have a documented history of gastric ulcers who also use NSAIDs chronically. Predictably, it is also useful in the management of hypersecretory conditions including Zollinger-Ellison syndrome. Lansoprazole is effective at eradicating H. pylori when used in conjunction with amoxicillin and clarithromycin (triple therapy) or with amoxicillin alone (dual therapy).
University of Utah Health Sciences Center, Salt Lake City, Utah, United States
Research Site, Norfolk, Virginia, United States
Research SIte, Springfield, Missouri, United States
Vanderbilt University Medical Center, Vanderbilt Digestive Disease Clinic, TVC, Room 1660, Nashville, Tennessee, United States
Osaka University Hospital, Suita, Osaka, Japan
Emory University School of Medicine, Atlanta, Georgia, United States
Research Site, Oklahoma City, Oklahoma, United States
Head and Neck Surgery Associates, Indianapolis, Indiana, United States
Stay informed with timely notifications on clinical trials, regulatory changes, and research advancements related to this medication.