MedPath

Lansoprazole

Generic Name
Lansoprazole
Brand Names
Prevacid, Prevpac
Drug Type
Small Molecule
Chemical Formula
C16H14F3N3O2S
CAS Number
103577-45-3
Unique Ingredient Identifier
0K5C5T2QPG

Overview

Lansoprazole marketed under the brand Prevacid, is a proton pump inhibitor (PPI) and is structurally classified as a substituted benzimidazole. It reduces gastric acid secretion by targeting gastric H,K-ATPase pumps and is thus effective at promoting healing in ulcerative diseases, and treating gastroesophageal reflux disease (GERD) along with other pathologies caused by excessive acid secretion.

Background

Lansoprazole marketed under the brand Prevacid, is a proton pump inhibitor (PPI) and is structurally classified as a substituted benzimidazole. It reduces gastric acid secretion by targeting gastric H,K-ATPase pumps and is thus effective at promoting healing in ulcerative diseases, and treating gastroesophageal reflux disease (GERD) along with other pathologies caused by excessive acid secretion.

Indication

Lansoprazole is used to reduce gastric acid secretion and is approved for short term treatment of active gastric ulcers, active duodenal ulcers, erosive reflux oesophagitis, symptomatic gastroesophageal reflux disease, and non-steroidal anti-inflammatory drug (NSAID) induced gastric and duodenal ulcers. It may be used in the maintenance and healing of several gastric conditions including duodenal ulcers, NSAID related gastric ulcers, and erosive esophagitis. Lansoprazole prevents recurrence of gastric ulcers in patients who have a documented history of gastric ulcers who also use NSAIDs chronically. Predictably, it is also useful in the management of hypersecretory conditions including Zollinger-Ellison syndrome. Lansoprazole is effective at eradicating H. pylori when used in conjunction with amoxicillin and clarithromycin (triple therapy) or with amoxicillin alone (dual therapy).

Associated Conditions

  • Duodenal Ulcer
  • Erosive Esophagitis
  • Helicobacter Pylori Infection
  • Symptomatic Gastroesophageal Reflux Disease (sGERD)
  • Ulcer Healing
  • Zollinger-Ellison Syndrome
  • Active Duodenal ulcer
  • Develop NSAID-induced gastric ulcers
  • Hypersecretory conditions
  • Maintenance of healing Erosive esophagitis

FDA Approved Products

Lansoprazole
Manufacturer:Camber Pharmaceuticals, Inc.
Route:ORAL
Strength:15 mg in 1 1
Approved: 2020/07/24
NDC:31722-570
LANSOPRAZOLE
Manufacturer:DIRECT RX
Route:ORAL
Strength:15 mg in 1 1
Approved: 2019/10/10
NDC:61919-245
Lansoprazole
Manufacturer:Dr.Reddy's Laboratories Ltd.
Route:ORAL
Strength:30 mg in 1 1
Approved: 2022/03/21
NDC:55111-399
Lansoprazole
Manufacturer:Dr.Reddy's Laboratories Ltd.
Route:ORAL
Strength:15 mg in 1 1
Approved: 2022/03/21
NDC:55111-398
Lansoprazole
Manufacturer:A-S Medication Solutions
Route:ORAL
Strength:30 mg in 1 1
Approved: 2022/03/21
NDC:50090-6830

Singapore Approved Products

No Singapore products found for this drug

Drug Development Updates

Stay informed with timely notifications on clinical trials and research advancements.

© Copyright 2025. All Rights Reserved by MedPath