Lansoprazole

Generic Name
Lansoprazole
Brand Names
Prevacid, Prevpac
Drug Type
Small Molecule
Chemical Formula
C16H14F3N3O2S
CAS Number
103577-45-3
Unique Ingredient Identifier
0K5C5T2QPG
Background

Lansoprazole marketed under the brand Prevacid, is a proton pump inhibitor (PPI) and is structurally classified as a substituted benzimidazole. It reduces gastric acid secretion by targeting gastric H,K-ATPase pumps and is thus effective at promoting healing in ulcerative diseases, and treating gastroesophageal reflux disease (GERD) along with other patholog...

Indication

Lansoprazole is used to reduce gastric acid secretion and is approved for short term treatment of active gastric ulcers, active duodenal ulcers, erosive reflux oesophagitis, symptomatic gastroesophageal reflux disease, and non-steroidal anti-inflammatory drug (NSAID) induced gastric and duodenal ulcers. It may be used in the maintenance and healing of sever...

Associated Conditions
Duodenal Ulcer, Erosive Esophagitis, Helicobacter Pylori Infection, Symptomatic Gastroesophageal Reflux Disease (sGERD), Ulcer Healing, Zollinger-Ellison Syndrome, Active Duodenal ulcer, Develop NSAID-induced gastric ulcers, Hypersecretory conditions, Maintenance of healing Erosive esophagitis
Associated Therapies
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Efficacy and Safety of Extended Release and Immediate Release Febuxostat in Participants With Gout

First Posted Date
2014-05-15
Last Posted Date
2016-11-03
Lead Sponsor
Takeda
Target Recruit Count
1790
Registration Number
NCT02139046

Efficacy and Safety of Extended Release and Immediate Release Febuxostat in Participants With Gout and Moderate Renal Impairment

First Posted Date
2014-05-01
Last Posted Date
2016-11-03
Lead Sponsor
Takeda
Target Recruit Count
189
Registration Number
NCT02128490
Locations
🇺🇸

Benny Green MD PA Family Practice, Little Rock, Arkansas, United States

🇺🇸

Long Beach Center for Clinical Research, Long Beach, California, United States

🇺🇸

Central Kentucy Reseach Associates, Lexington, Kentucky, United States

and more 8 locations

Long-term Use of Takepron Capsules on the Prevention of Recurrence of Gastric/Duodenal Ulcer in Patients Receiving Low-dose Aspirin

Completed
Conditions
Interventions
First Posted Date
2014-03-31
Last Posted Date
2016-11-04
Lead Sponsor
Takeda
Target Recruit Count
3366
Registration Number
NCT02099682

Long-term Use of Takepron on the Prevention of Recurrence of Gastric/Duodenal Ulcer in Patients Receiving Non-steroidal Anti-inflammatory Drugs

Completed
Conditions
Interventions
First Posted Date
2014-03-31
Last Posted Date
2016-10-27
Lead Sponsor
Takeda
Target Recruit Count
3502
Registration Number
NCT02099708

Effect of Proton Pump Inhibitors on Endothelial Function

Phase 1
Completed
Conditions
Interventions
First Posted Date
2013-12-27
Last Posted Date
2022-08-23
Lead Sponsor
Stanford University
Target Recruit Count
21
Registration Number
NCT02022280
Locations
🇺🇸

Stanford University, Stanford, California, United States

Lansoprazole Tablets Special Drug Use Surveillance Gastroesophageal Reflux Disease With Dyspepsia Symptoms

First Posted Date
2013-11-21
Last Posted Date
2016-09-27
Lead Sponsor
Takeda
Target Recruit Count
14965
Registration Number
NCT01990339

Lansoprazole in Preterm Infants With Gastroesophageal Reflux (GER)

First Posted Date
2013-09-20
Last Posted Date
2014-11-19
Lead Sponsor
Seoul National University Hospital
Target Recruit Count
12
Registration Number
NCT01946971
Locations
🇰🇷

Seoul National University Hospital, Seoul, Korea, Republic of

Lansoprazole in Preterm Infants With Reflux

Phase 2
Completed
Conditions
Interventions
First Posted Date
2013-01-29
Last Posted Date
2013-09-13
Lead Sponsor
Seoul National University Hospital
Target Recruit Count
5
Registration Number
NCT01778101
Locations
🇰🇷

Seoul National University Children's Hospital, Seoul, Korea, Republic of

A Study of LY2940680 in Healthy Participants

First Posted Date
2012-09-07
Last Posted Date
2019-10-21
Lead Sponsor
Eli Lilly and Company
Target Recruit Count
30
Registration Number
NCT01681186
Locations
🇺🇸

For additional information regarding investigative sites for this trial, contact 1-877-CTLILLY (1-877-285-4559, 1-317-615-4559) Mon - Fri from 9 AM to 5 PM Eastern Time (UTC/GMT - 5 hours, EST), or speak with your personal physician., Dallas, Texas, United States

Bismuth Improves the Efficacy of Levofloxacin-containing Triple Therapy for Helicobacter Pylori Treatment

First Posted Date
2012-08-17
Last Posted Date
2012-12-13
Lead Sponsor
Shanghai Jiao Tong University School of Medicine
Target Recruit Count
161
Registration Number
NCT01667718
Locations
🇨🇳

Shanghai Jiao-Tong University School of Medicine Renji Hospital, Shanghai, Shanghai, China

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