• Turnstone Biologics is prioritizing its clinical program, TIDAL-01, a Selected TIL therapy, and streamlining operations to extend its cash runway into the second quarter of 2026.
• The company is reducing its workforce by approximately 60% as part of a strategic realignment to focus on clinical development and manufacturing efforts.
• Initial Phase 1 data from the STARLING trial supports the biological hypothesis for TIL selection, showcasing a complete response in a heavily pre-treated MSS-CRC patient.
• Leadership transitions include Ines Verdon assuming leadership of clinical activities and Michael Fitch overseeing manufacturing, with other changes in finance and operations.