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Azelaic acid

Generic Name
Azelaic acid
Brand Names
Azelex, Finacea
Drug Type
Small Molecule
Chemical Formula
C9H16O4
CAS Number
123-99-9
Unique Ingredient Identifier
F2VW3D43YT
Background

Azelaic acid is a saturated dicarboxylic acid found naturally in wheat, rye, and barley. It is also produced by Malassezia furfur, also known as Pityrosporum ovale, which is a species of fungus that is normally found on human skin. Azelaic acid is effective against a number of skin conditions, such as mild to moderate acne, when applied topically in a cream formulation of 20%. It works in part by stopping the growth of skin bacteria that cause acne, and by keeping skin pores clear. Azelaic acid's antimicrobial action may be attributable to inhibition of microbial cellular protein synthesis.

Indication

For the topical treatment of mild-to-moderate inflammatory acne vulgaris.

Associated Conditions
Acne Vulgaris, Inflammatory lesions caused by rosacea, Susceptible Bacterial Infections
Associated Therapies
Nutritional supplementation

Rosacea in Patients of Color: Experts Call for Better Recognition and Diagnosis

• Rosacea affects approximately 40 million patients of color globally, challenging the traditional view of it being primarily a condition affecting those of Northern European descent. • Diagnostic challenges in darker skin tones often lead to delayed treatment, with most patients of color experiencing symptoms for over a year before receiving proper diagnosis. • Current treatment approaches remain consistent across all skin types, with newer medications like ivermectin cream 1%, minocycline foam 1.5%, and microencapsulated benzoyl peroxide 5% showing promise.
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