Tetracycline

Tetracycline is a broad spectrum polyketide antibiotic produced by the Streptomyces genus of Actinobacteria. It exerts a bacteriostatic effect on bacteria by binding reversible to the bacterial 30S ribosomal subunit and blocking incoming aminoacyl tRNA from binding to the ribosome acceptor site. It also binds to some extent to the bacterial 50S ribosomal subunit and may alter the cytoplasmic membrane causing intracellular components to leak from bacterial cells. The FDA withdrew its approval for the use of all liquid oral drug products formulated for pediatric use containing tetracycline in a concentration greater than 25 mg/ml. Other formulations of tetracycline continue to be used.

Tetracycline is a broad spectrum polyketide antibiotic produced by the Streptomyces genus of Actinobacteria. It exerts a bacteriostatic effect on bacteria by binding reversible to the bacterial 30S ribosomal subunit and blocking incoming aminoacyl tRNA from binding to the ribosome acceptor site. It also binds to some extent to the bacterial 50S ribosomal subunit and may alter the cytoplasmic membrane causing intracellular components to leak from bacterial cells. The FDA withdrew its approval for the use of all liquid oral drug products formulated for pediatric use containing tetracycline in a concentration greater than 25 mg/ml. Other formulations of tetracycline continue to be used.

Used to treat bacterial infections such as Rocky Mountain spotted fever, typhus fever, tick fevers, Q fever, rickettsialpox and Brill-Zinsser disease. May be used to treat infections caused by Chlamydiae spp., B. burgdorferi (Lyme disease), and upper respiratory infections caused by typical (S. pneumoniae, H. influenzae, and M. catarrhalis) and atypical organisms (C. pneumoniae, M. pneumoniae, L. pneumophila). May also be used to treat acne. Tetracycline may be an alternative drug for people who are allergic to penicillin.

• Acinetobacter Infections
• Actinomycosis
• Anthrax
• Bacterial Infections
• Bartonellosis
• Brucellosis
• Campylobacter Infection
• Chancroid
• Chlamydial Infections
• Cholera (Disorder)
• Clostridium Infections
• Conjunctivitis, Inclusion
• Cystitis
• Endometritis
• Entamoebic histolytica infection
• Escherichia infections
• Granuloma Inguinale
• Helicobacter Pylori Infection
• Infection
• Infection, Bacteroides
• Klebsiella Infections
• Listeria infection
• Lower respiratory tract infection bacterial
• Lymphogranuloma Venereum
• Necrotizing ulcerative gingivostomatitis
• Neisseria Gonorrhoeae Infection
• Nephritis
• Ornithosis
• Plague
• Prostatitis
• Psittacosis
• Q Fever
• Relapsing Fever
• Rickettsialpox
• Rocky Mountain Spotted Fever
• Rosacea
• Severe Acne
• Shigella Infection
• Skin Infections caused by Staphylococcus Aureus
• Skin and Subcutaneous Tissue Bacterial Infections
• Syphilis
• Trachoma
• Tularemia
• Typhus
• Upper respiratory tract infection bacterial
• Urinary Tract Infection
• Yaws
• Grade 1, grade 2, grade 3, grade 4 Urinary Tract Infection