MedPath

Hydrogen peroxide

Generic Name
Hydrogen peroxide
Brand Names
Eskata, Orajel Mouth Sore Rinse
Drug Type
Small Molecule
Chemical Formula
H2O2
CAS Number
7722-84-1
Unique Ingredient Identifier
BBX060AN9V

Overview

Hydrogen peroxide is the simplest peroxide with a chemical formula H2O2. Hydrogen peroxide is an unstable compound in the presence of a base or catalyst, and is typically stored with a stabilizer in a weakly acidic solution. If heated to its boiling point, it may undergo potentially explosive thermal decomposition. Hydrogen peroxide is formed in the body of mammals during reduction of oxygen either directly in a two-electron transfer reaction . As a natural product of metabolism, it readily undergoes decomposition by catalase in normal cells . Due to its potent and broad-spectrum antimicrobial actions, hydrogen peroxide is used in both liquid and gas form for preservative, disinfection and sterilization applications as an oxidative biocide . It is used in industrial and cosmetic applications as a bleaching agent. Hydrogen peroxide is also considered as a generally recognized as safe compound by the FDA ; it is used as an antimicrobial agent in starch and cheese products, and as an oxidizing and reducing agent in products containing dried eggs, dried egg whites, and dried egg yolks.

Background

Hydrogen peroxide is the simplest peroxide with a chemical formula H2O2. Hydrogen peroxide is an unstable compound in the presence of a base or catalyst, and is typically stored with a stabilizer in a weakly acidic solution. If heated to its boiling point, it may undergo potentially explosive thermal decomposition. Hydrogen peroxide is formed in the body of mammals during reduction of oxygen either directly in a two-electron transfer reaction . As a natural product of metabolism, it readily undergoes decomposition by catalase in normal cells . Due to its potent and broad-spectrum antimicrobial actions, hydrogen peroxide is used in both liquid and gas form for preservative, disinfection and sterilization applications as an oxidative biocide . It is used in industrial and cosmetic applications as a bleaching agent. Hydrogen peroxide is also considered as a generally recognized as safe compound by the FDA ; it is used as an antimicrobial agent in starch and cheese products, and as an oxidizing and reducing agent in products containing dried eggs, dried egg whites, and dried egg yolks.

Indication

Indicated to be used as a disinfectant and sterilizer.

Associated Conditions

  • Ear infection bacterial
  • Seborrheic Keratosis (SK)
  • Impacted ear wax
  • Superficial skin infections

FDA Approved Products

Eskata
Manufacturer:Aclaris Therapeutics, Inc.
Route:TOPICAL
Strength:40 mg in 100 mg
Approved: 2019/03/27
NDC:71180-002
Eskata
Manufacturer:Aclaris Therapeutics, Inc.
Route:TOPICAL
Strength:40 mg in 100 mg
Approved: 2019/03/27
NDC:71180-001
Hydrogen Peroxide 3 Percent
Manufacturer:Good Sense (Geiss, Destin & Dunn, Inc.)
Route:TOPICAL
Strength:2.65 mL in 100 mL
Approved: 2025/03/03
NDC:50804-156
Hydrogen Peroxide
Manufacturer:GoBrands, Inc.
Route:TOPICAL
Strength:30 mg in 1 mL
Approved: 2025/03/03
NDC:82501-0871
Aplicare
Manufacturer:Aplicare Products LLC
Route:TOPICAL
Strength:3 mL in 100 mL
Approved: 2025/04/18
NDC:52380-1013

Singapore Approved Products

No Singapore products found for this drug

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