Overview
Hydrogen peroxide is the simplest peroxide with a chemical formula H2O2. Hydrogen peroxide is an unstable compound in the presence of a base or catalyst, and is typically stored with a stabilizer in a weakly acidic solution. If heated to its boiling point, it may undergo potentially explosive thermal decomposition. Hydrogen peroxide is formed in the body of mammals during reduction of oxygen either directly in a two-electron transfer reaction . As a natural product of metabolism, it readily undergoes decomposition by catalase in normal cells . Due to its potent and broad-spectrum antimicrobial actions, hydrogen peroxide is used in both liquid and gas form for preservative, disinfection and sterilization applications as an oxidative biocide . It is used in industrial and cosmetic applications as a bleaching agent. Hydrogen peroxide is also considered as a generally recognized as safe compound by the FDA ; it is used as an antimicrobial agent in starch and cheese products, and as an oxidizing and reducing agent in products containing dried eggs, dried egg whites, and dried egg yolks.
Indication
Indicated to be used as a disinfectant and sterilizer.
Associated Conditions
- Ear infection bacterial
- Seborrheic Keratosis (SK)
- Impacted ear wax
- Superficial skin infections
Clinical Trials
Title | Posted | Study ID | Phase | Status | Sponsor |
|---|---|---|---|---|---|
2022/10/06 | Phase 1 | Not yet recruiting | |||
2021/08/27 | Early Phase 1 | Recruiting | |||
2020/12/09 | Phase 4 | Completed | |||
2019/05/10 | Phase 2 | Recruiting | Institute of Cancer Research, United Kingdom | ||
2019/01/23 | Phase 3 | Completed | |||
2018/09/27 | Phase 3 | Completed | |||
2018/09/19 | Early Phase 1 | Completed | |||
2018/05/25 | Phase 2 | Completed | |||
2017/05/11 | Phase 2 | Completed | |||
2017/01/12 | Phase 4 | Completed | University of Campinas, Brazil |
FDA Drug Approvals
Approved Product | Manufacturer | NDC Code | Route | Strength | Effective Date |
|---|---|---|---|---|---|
| Aclaris Therapeutics, Inc. | 71180-001 | TOPICAL | 40 mg in 100 mg | 3/27/2019 | |
| Chain Drug Marketing Association, Inc | 83324-290 | TOPICAL | 30 mg in 1 g | 5/26/2025 | |
| Cardinal Health, 110 dba Leader | 70000-0022 | TOPICAL | 3 mL in 100 mL | 3/31/2025 | |
| Amerifoods Trading Co | 61504-871 | TOPICAL | 30 mg in 1 mL | 4/9/2025 | |
| Aclaris Therapeutics, Inc. | 71180-002 | TOPICAL | 40 mg in 100 mg | 3/27/2019 | |
| Amazon.Com Services LLC | 72288-871 | TOPICAL | 30 mg in 1 mL | 5/20/2025 | |
| Aplicare Products LLC | 52380-1013 | TOPICAL | 3 mL in 100 mL | 4/18/2025 | |
| GoBrands, Inc. | 82501-0871 | TOPICAL | 30 mg in 1 mL | 3/3/2025 | |
| TOP CARE (Topco Associates LLC) | 36800-214 | TOPICAL | 2.65 mL in 100 mL | 4/9/2025 | |
| Good Sense (Geiss, Destin & Dunn, Inc.) | 50804-156 | TOPICAL | 2.65 mL in 100 mL | 3/3/2025 |
EMA Drug Approvals
Approved Product | Authorization Holder | Status | Issued Date |
|---|---|---|---|
| No EMA approvals found for this drug. | |||
HSA Drug Approvals
Approved Product | Manufacturer | Approval Number | Dosage Form | Strength | Approval Date |
|---|---|---|---|---|---|
| No HSA approvals found for this drug. | |||||
NMPA Drug Approvals
Approved Product | Company | Approval Number | Drug Type | Dosage Form | Approval Date |
|---|---|---|---|---|---|
| No NMPA approvals found for this drug. | |||||
PPB Drug Approvals
Approved Product | Registration No. | Company | Licence No. | Strength | Registration Date |
|---|---|---|---|---|---|
| HYDROGEN PEROXIDE SOLN 6% STABILIZED | N/A | N/A | N/A | 5/5/1982 | |
| VALIANT SOLUTION 6% (20 VOLUME) | N/A | N/A | N/A | 4/29/1986 | |
| HYDROGEN PEROXIDE SOLUTION 3% 'JEN SHENG' | N/A | N/A | N/A | 6/8/1999 |
TGA Drug Approvals
Approved Product | ARTG ID | Sponsor | Registration Type | Status | Registration Date |
|---|---|---|---|---|---|
| Hydrogen Peroxide 60mg/g (6%) | 14694 | Medicine | A | 10/25/1991 | |
| PEROXYL ORAL CLEANSER hydrogen peroxide 1.5% w/v solution bottle | 78063 | Medicine | A | 4/12/2001 | |
| Hydrogen Peroxide 30mg/g (3%) solution bottle | 14695 | Medicine | A | 10/25/1991 | |
| HYDROGEN PEROXIDE SOLUTION 3% BP | 62624 | Medicine | A | 12/5/1997 | |
| GOLD CROSS HYDROGEN PEROXIDE 3%w/v solution bottle | 27200 | Medicine | A | 11/11/1991 | |
| GOLD CROSS HYDROGEN PEROXIDE 6%w/v solution bottle | 27241 | Medicine | A | 11/11/1991 | |
| HYDROGEN PEROXIDE 3% hydrogen peroxide 3% w/v topical solution ampoule | 11385 | Medicine | A | 8/13/1991 | |
| CRYSTADERM hydrogen peroxide 1% w/w cream tube | 257332 | Medicine | A | 8/24/2015 | |
| Hydrogen Peroxide (3%) Irrigation | 279135 | Medicine | A | 8/15/2016 | |
| HYDROGEN PEROXIDE Solution 10 Vol (3%) solution bottle | 11383 | Medicine | A | 8/13/1991 |
Health Canada Drug Approvals
Approved Product | Company | DIN | Dosage Form | Strength | Market Date |
|---|---|---|---|---|---|
| ORAJEL PERIOSEPTIC RINSE - 1.5% | del pharmaceutics (canada) inc. | 02229965 | Mouthwash/Gargle - Oral | 1.5 % | 10/21/1997 |
| HIOXYL CREAM | seaford pharmaceuticals inc | 02239473 | Cream - Topical | 1.5 % | 5/31/1999 |
| HYDROGEN PEROXIDE SOLUTION 3% | h.j. sutton industries ltd. | 01995189 | Solution - Topical | 3 % | 12/31/1993 |
| HYDROGEN PEROXIDE LIQ 10VOL | stanley pharmaceuticals, a division of vita health products inc. | 00179086 | Liquid - Topical | 3 % | 12/31/1965 |
| HYDROGEN PEROXIDE LIQ 6% | d.c. labs limited | 00094005 | Liquid - Topical | 6 % | 12/31/1951 |
| HYDROGEN PEROXIDE TOPICAL SOL USP 3% | lawton's drug stores ltd. | 00728764 | Liquid - Topical | 3 % | 12/31/1987 |
| HYDROGEN PEROXIDE TOPICAL SOLUTION USP | kolmar canada inc. | 00723835 | Solution - Topical | 3 % | 12/31/1986 |
| HYDROGEN PEROXIDE SOLUTION 3% | ingram and bell inc. | 00120510 | Liquid - Topical | 3 % | 12/31/1951 |
| PERIOSELECT HYDROGEN PEROXIDE SOLUTION 1.7% | sultan healthcare | 00897604 | Liquid - Dental | 1.7 % | 12/31/1992 |
| HYDROGEN PEROXIDE TOP SOL 3% 10VOL ANTI | scott chemical canada | 01948695 | Liquid - Topical | 3 % | 12/31/1992 |
CIMA AEMPS Drug Approvals
Approved Product | Company | Registration Number | Pharmaceutical Form | Prescription Type | Status |
|---|---|---|---|---|---|
| No CIMA AEMPS (Spain) approvals found for this drug. | |||||
Philippines FDA Drug Approvals
Approved Product | Company | License Number | Dosage Form | Strength | Approval Date |
|---|---|---|---|---|---|
| No Philippines FDA approvals found for this drug. | |||||
Saudi SFDA Drug Approvals
Approved Product | Company | License Number | Dosage Form | Strength | Approval Date |
|---|---|---|---|---|---|
| No Saudi SFDA approvals found for this drug. | |||||
Malaysia NPRA Drug Approvals
Approved Product | Company | Registration Number | Dosage Form | Strength | Approval Date |
|---|---|---|---|---|---|
| No Malaysia NPRA approvals found for this drug. | |||||
UK EMC Drug Information
Medicine Name | MA Holder | MA Number | Pharmaceutical Form | Active Ingredient | Authorization Date |
|---|---|---|---|---|---|
| No UK EMC drug information found for this drug. | |||||
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