Overview
Hydrogen peroxide is the simplest peroxide with a chemical formula H2O2. Hydrogen peroxide is an unstable compound in the presence of a base or catalyst, and is typically stored with a stabilizer in a weakly acidic solution. If heated to its boiling point, it may undergo potentially explosive thermal decomposition. Hydrogen peroxide is formed in the body of mammals during reduction of oxygen either directly in a two-electron transfer reaction . As a natural product of metabolism, it readily undergoes decomposition by catalase in normal cells . Due to its potent and broad-spectrum antimicrobial actions, hydrogen peroxide is used in both liquid and gas form for preservative, disinfection and sterilization applications as an oxidative biocide . It is used in industrial and cosmetic applications as a bleaching agent. Hydrogen peroxide is also considered as a generally recognized as safe compound by the FDA ; it is used as an antimicrobial agent in starch and cheese products, and as an oxidizing and reducing agent in products containing dried eggs, dried egg whites, and dried egg yolks.
Indication
Indicated to be used as a disinfectant and sterilizer.
Associated Conditions
- Ear infection bacterial
- Seborrheic Keratosis (SK)
- Impacted ear wax
- Superficial skin infections
Clinical Trials
Title | Posted | Study ID | Phase | Status | Sponsor |
|---|---|---|---|---|---|
2022/10/06 | Phase 1 | Not yet recruiting | |||
2021/08/27 | Early Phase 1 | Recruiting | |||
2020/12/09 | Phase 4 | Completed | |||
2019/05/10 | Phase 2 | Recruiting | Institute of Cancer Research, United Kingdom | ||
2019/01/23 | Phase 3 | Completed | |||
2018/09/27 | Phase 3 | Completed | |||
2018/09/19 | Early Phase 1 | Completed | |||
2018/05/25 | Phase 2 | Completed | |||
2017/05/11 | Phase 2 | Completed | |||
2017/01/12 | Phase 4 | Completed | University of Campinas, Brazil |
FDA Drug Approvals
Approved Product | Manufacturer | NDC Code | Route | Strength | Effective Date |
|---|---|---|---|---|---|
| Aclaris Therapeutics, Inc. | 71180-001 | TOPICAL | 40 mg in 100 mg | 3/27/2019 | |
| Chain Drug Marketing Association, Inc | 83324-290 | TOPICAL | 30 mg in 1 g | 5/26/2025 | |
| Cardinal Health, 110 dba Leader | 70000-0022 | TOPICAL | 3 mL in 100 mL | 3/31/2025 | |
| Amerifoods Trading Co | 61504-871 | TOPICAL | 30 mg in 1 mL | 4/9/2025 | |
| Aclaris Therapeutics, Inc. | 71180-002 | TOPICAL | 40 mg in 100 mg | 3/27/2019 | |
| Amazon.Com Services LLC | 72288-871 | TOPICAL | 30 mg in 1 mL | 5/20/2025 | |
| Aplicare Products LLC | 52380-1013 | TOPICAL | 3 mL in 100 mL | 4/18/2025 | |
| GoBrands, Inc. | 82501-0871 | TOPICAL | 30 mg in 1 mL | 3/3/2025 | |
| TOP CARE (Topco Associates LLC) | 36800-214 | TOPICAL | 2.65 mL in 100 mL | 4/9/2025 | |
| Good Sense (Geiss, Destin & Dunn, Inc.) | 50804-156 | TOPICAL | 2.65 mL in 100 mL | 3/3/2025 |
EMA Drug Approvals
Approved Product | Authorization Holder | Status | Issued Date |
|---|---|---|---|
| No EMA approvals found for this drug. | |||
HSA Drug Approvals
Approved Product | Manufacturer | Approval Number | Dosage Form | Strength | Approval Date |
|---|---|---|---|---|---|
| No HSA approvals found for this drug. | |||||
NMPA Drug Approvals
Approved Product | Company | Approval Number | Drug Type | Dosage Form | Approval Date |
|---|---|---|---|---|---|
| Hydrogen Peroxide Solution | 国药准字H43020895 | 化学药品 | 溶液剂(外用) | 8/11/2020 | |
| Hydrogen Peroxide Solution | 国药准字H51022878 | 化学药品 | 溶液剂 | 2/25/2020 | |
| Hydrogen Peroxide Solution | 国药准字H23021977 | 化学药品 | 溶液剂 | 4/28/2020 | |
| Hydrogen Peroxide Solution | 国药准字H23020781 | 化学药品 | 溶液剂 | 12/7/2020 | |
| Hydrogen Peroxide Solution | 国药准字H34021560 | 化学药品 | 溶液剂 | 3/14/2022 | |
| Hydrogen Peroxide Solution | 国药准字H21022270 | 化学药品 | 溶液剂 | 10/21/2020 | |
| Hydrogen Peroxide Solution | 国药准字H13024156 | 化学药品 | 液体剂 | 3/18/2020 | |
| Hydrogen Peroxide Solution | 国药准字H43020244 | 化学药品 | 涂剂 | 12/12/2019 | |
| Hydrogen Peroxide Solution | 国药准字H13022556 | 化学药品 | 溶液剂 | 8/17/2020 | |
| Hydrogen Peroxide Solution | 国药准字H21024402 | 化学药品 | 溶液剂 | 7/2/2021 |
PPB Drug Approvals
Approved Product | Registration No. | Company | Licence No. | Strength | Registration Date |
|---|---|---|---|---|---|
| HYDROGEN PEROXIDE SOLN 6% STABILIZED | N/A | N/A | N/A | 5/5/1982 | |
| VALIANT SOLUTION 6% (20 VOLUME) | N/A | N/A | N/A | 4/29/1986 | |
| HYDROGEN PEROXIDE SOLUTION 3% 'JEN SHENG' | N/A | N/A | N/A | 6/8/1999 |
TGA Drug Approvals
Approved Product | ARTG ID | Sponsor | Registration Type | Status | Registration Date |
|---|---|---|---|---|---|
| Hydrogen Peroxide 60mg/g (6%) | 14694 | Medicine | A | 10/25/1991 | |
| PEROXYL ORAL CLEANSER hydrogen peroxide 1.5% w/v solution bottle | 78063 | Medicine | A | 4/12/2001 | |
| Hydrogen Peroxide 30mg/g (3%) solution bottle | 14695 | Medicine | A | 10/25/1991 | |
| HYDROGEN PEROXIDE SOLUTION 3% BP | 62624 | Medicine | A | 12/5/1997 | |
| GOLD CROSS HYDROGEN PEROXIDE 3%w/v solution bottle | 27200 | Medicine | A | 11/11/1991 | |
| GOLD CROSS HYDROGEN PEROXIDE 6%w/v solution bottle | 27241 | Medicine | A | 11/11/1991 | |
| HYDROGEN PEROXIDE 3% hydrogen peroxide 3% w/v topical solution ampoule | 11385 | Medicine | A | 8/13/1991 | |
| CRYSTADERM hydrogen peroxide 1% w/w cream tube | 257332 | Medicine | A | 8/24/2015 | |
| Hydrogen Peroxide (3%) Irrigation | 279135 | Medicine | A | 8/15/2016 | |
| HYDROGEN PEROXIDE Solution 10 Vol (3%) solution bottle | 11383 | Medicine | A | 8/13/1991 |
Help Us Improve
Your feedback helps us provide better drug information and insights.