Chlorpromazine

Generic Name
Chlorpromazine
Brand Names
-
Drug Type
Small Molecule
Chemical Formula
C17H19ClN2S
CAS Number
50-53-3
Unique Ingredient Identifier
U42B7VYA4P
Background

The prototypical phenothiazine antipsychotic drug. Like the other drugs in this class, chlorpromazine's antipsychotic actions are thought to be due to long-term adaptation by the brain to blocking dopamine receptors. Chlorpromazine has several other actions and therapeutic uses, including as an antiemetic and in the treatment of intractable hiccup.

Indication

For the treatment of schizophrenia; to control nausea and vomiting; for relief of restlessness and apprehension before surgery; for acute intermittent porphyria; as an adjunct in the treatment of tetanus; to control the manifestations of the manic type of manic-depressive illness; for relief of intractable hiccups; for the treatment of severe behavioral prob...

Associated Conditions
Acute Intermittent Porphyria (AIP), Apprehension, Defiant Disorder, Oppositional, Intractable hiccups, Mania, Nausea and vomiting, Restlessness, Schizophrenia, Tetanus, Severe behavioural problems, Short term Hyperactivity
Associated Therapies
-
Clinical Trials
Related News

Comparison of Combination Olanzapine+Lithium or Chlorpromazine+Lithium in Treatment of First Manic Episode With Psychotic Features

First Posted Date
2005-09-20
Last Posted Date
2018-08-31
Lead Sponsor
Melbourne Health
Target Recruit Count
83
Registration Number
NCT00202293
Locations
🇦🇺

ORYGEN Youth Health, Parkville, Victoria, Australia

Clozapine Versus Chlorpromazine for Treatment-Unresponsive Schizophrenia

Phase 4
Terminated
Conditions
Schizophrenia
First Posted Date
2005-09-15
Last Posted Date
2015-04-07
Lead Sponsor
Harvard Medical School (HMS and HSDM)
Target Recruit Count
66
Registration Number
NCT00169039
Locations
🇺🇸

Commonwealth Research Center, Jamaica Plain, Massachusetts, United States

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