Esomeprazole
- Generic Name
- Esomeprazole
- Brand Names
- Nexium, Vimovo, Nexium Control
- Drug Type
- Small Molecule
- Chemical Formula
- C17H19N3O3S
- CAS Number
- 119141-88-7
- Unique Ingredient Identifier
- N3PA6559FT
- Background
Esomeprazole, sold under the brand name Nexium, is a proton pump inhibitor (PPI) medication used for the management of gastroesophageal reflux disease (GERD), for gastric protection to prevent recurrence of stomach ulcers or gastric damage from chronic use of NSAIDs, and for the treatment of pathological hypersecretory conditions including Zollinger-Ellison ...
- Indication
Esomeprazole is indicated for the treatment of acid-reflux disorders including healing and maintenance of erosive esophagitis, and symptomatic gastroesophageal reflux disease (GERD), peptic ulcer disease, H. pylori eradication, prevention of gastrointestinal bleeds with NSAID use, and for the long-term treatment of pathological hypersecretory conditions incl...
- Associated Conditions
- Duodenal Ulcer, Erosive Esophagitis, Gastro-esophageal Reflux Disease (GERD), Heartburn, Helicobacter Pylori Infection, Stress Ulcers, Upper Gastrointestinal Hemorrhage, Zollinger-Ellison Syndrome, Acute benign gastric ulcers, Develop NSAID-induced gastric ulcers, Maintenance of healing Erosive esophagitis, Postendoscopy Bleeding
- Associated Therapies
- -
Safety and PK of Ceftibuten-ledaborbactam Etzadroxil Fixed-dose Combination
- Conditions
- Interventions
- First Posted Date
- 2024-12-13
- Last Posted Date
- 2024-12-18
- Lead Sponsor
- Venatorx Pharmaceuticals, Inc.
- Target Recruit Count
- 46
- Registration Number
- NCT06733675
Indonesian Study of Vonoprazan Vs Esomeprazole in Erosive Esophagitis
- Conditions
- Interventions
- First Posted Date
- 2024-12-06
- Last Posted Date
- 2024-12-17
- Lead Sponsor
- Indonesia University
- Target Recruit Count
- 216
- Registration Number
- NCT06720610
- Locations
- 🇮🇩
Cipto Mangunkusumo Hospital, Jakarta Pusat, DKI Jakarta, Indonesia
🇮🇩Hermina Kemayoran Hospital, Jakarta Pusat, DKI Jakarta, Indonesia
🇮🇩Hermina Bekasi Hospital, Bekasi, Jawa Barat, Indonesia
Relative Bioavailability of NX-5948 Tablets Vs Capsules and the Effect of Covariates on the PK of NX-5948 Tablets
- Conditions
- Interventions
- First Posted Date
- 2024-12-04
- Last Posted Date
- 2024-12-19
- Lead Sponsor
- Nurix Therapeutics, Inc.
- Target Recruit Count
- 18
- Registration Number
- NCT06717269
- Locations
- 🇺🇸
Celerion, Lincoln, Nebraska, United States
Study on the Efficacy and Safety of Berberine, Minocycline, Esomeprazole, and Colloidal Bismuth Quadruple Therapy in the Initial Treatment of Helicobacter Pylori.
- Conditions
- Interventions
- First Posted Date
- 2024-09-19
- Last Posted Date
- 2024-09-19
- Lead Sponsor
- Xijing Hospital of Digestive Diseases
- Target Recruit Count
- 548
- Registration Number
- NCT06603688
- Locations
- 🇨🇳
Xijing Hosipital of Digestive Disease, Xian, Shaanxi, China
Efficacy and Safety of Vonorasan Versus Esomeprazole in the Treatment of Ulcers After Endoscopic Submucosal Dissection
- First Posted Date
- 2024-07-29
- Last Posted Date
- 2024-07-29
- Lead Sponsor
- Shicai Ye
- Target Recruit Count
- 196
- Registration Number
- NCT06526455
- Locations
- 🇨🇳
Yellow River Sanmenxia Hospital, Sanmenxia, Henan, China
🇨🇳The First Affiliated Hospital of Jinan University, Guangzhou, Guangdong, China
🇨🇳Maoming People's Hospital, Maoming, Guangdong, China
Study on The Efficacy and Safety of Vonoprazan-containing Berberine Triple Therapy in Helicobacter Pylori First-Line Eradication
- Conditions
- Interventions
- First Posted Date
- 2024-07-23
- Last Posted Date
- 2024-07-23
- Lead Sponsor
- Xijing Hospital of Digestive Diseases
- Target Recruit Count
- 558
- Registration Number
- NCT06514274
- Locations
- 🇨🇳
Xijing Hosipital of Digestive Disease, Xi'an, Shaanxi, China
A Study in Healthy Men to Test Whether Esomeprazole Influences the Amount of BI 3000202 in the Blood
- First Posted Date
- 2024-05-17
- Last Posted Date
- 2024-11-18
- Lead Sponsor
- Boehringer Ingelheim
- Target Recruit Count
- 15
- Registration Number
- NCT06419660
- Locations
- 🇩🇪
Humanpharmakologisches Zentrum Biberach, Biberach, Germany
A Study to Learn About How Food and Esomeprazole Affect the Level of BAY2927088 in the Blood When Taken Together in Healthy Participants
- Conditions
- Interventions
- First Posted Date
- 2024-04-22
- Last Posted Date
- 2024-07-05
- Lead Sponsor
- Bayer
- Target Recruit Count
- 21
- Registration Number
- NCT06378658
- Locations
- 🇺🇸
Parexel Baltimore - Early Phase Clinical Unit, Baltimore, Maryland, United States
A Trial to Evaluate the Effect of Esomeprazole on the Pharmacokinetics of Emraclidine in Healthy Adult Participants
- First Posted Date
- 2024-04-15
- Last Posted Date
- 2024-07-24
- Lead Sponsor
- Cerevel Therapeutics, LLC
- Target Recruit Count
- 20
- Registration Number
- NCT06366243
- Locations
- 🇺🇸
Dilworth, Minnesota, Dilworth, Minnesota, United States
Metformin and Esomeprazole in Preterm Pre-eclampsia
- Conditions
- Interventions
- First Posted Date
- 2024-04-11
- Last Posted Date
- 2024-04-11
- Lead Sponsor
- Christiana Care Health Services
- Target Recruit Count
- 4
- Registration Number
- NCT06359015
- Locations
- 🇺🇸
Christianacare Health System, Newark, Delaware, United States
Drug Development Updates
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