Esomeprazole
- Generic Name
- Esomeprazole
- Brand Names
- Nexium, Vimovo, Nexium Control
- Drug Type
- Small Molecule
- Chemical Formula
- C17H19N3O3S
- CAS Number
- 119141-88-7
- Unique Ingredient Identifier
- N3PA6559FT
- Background
Esomeprazole, sold under the brand name Nexium, is a proton pump inhibitor (PPI) medication used for the management of gastroesophageal reflux disease (GERD), for gastric protection to prevent recurrence of stomach ulcers or gastric damage from chronic use of NSAIDs, and for the treatment of pathological hypersecretory conditions including Zollinger-Ellison ...
- Indication
Esomeprazole is indicated for the treatment of acid-reflux disorders including healing and maintenance of erosive esophagitis, and symptomatic gastroesophageal reflux disease (GERD), peptic ulcer disease, H. pylori eradication, prevention of gastrointestinal bleeds with NSAID use, and for the long-term treatment of pathological hypersecretory conditions incl...
- Associated Conditions
- Duodenal Ulcer, Erosive Esophagitis, Gastro-esophageal Reflux Disease (GERD), Heartburn, Helicobacter Pylori Infection, Stress Ulcers, Upper Gastrointestinal Hemorrhage, Zollinger-Ellison Syndrome, Acute benign gastric ulcers, Develop NSAID-induced gastric ulcers, Maintenance of healing Erosive esophagitis, Postendoscopy Bleeding
- Associated Therapies
- -
High Dose of Dual Therapy Plus Bismuth for Helicobacter Pylori Treatment
- Conditions
- Interventions
- First Posted Date
- 2018-01-23
- Last Posted Date
- 2018-11-05
- Lead Sponsor
- Shanghai Jiao Tong University School of Medicine
- Target Recruit Count
- 160
- Registration Number
- NCT03405584
- Locations
- šØš³
Renji Hospital, School of Medicine, Shanghai Jiao Tong University, Shanghai, Shanghai, China
Comparison of Two Novel First-line Anti-Helicobacter Pylori Therapy
- Conditions
- Interventions
- First Posted Date
- 2017-12-26
- Last Posted Date
- 2019-01-30
- Lead Sponsor
- Chang Gung Memorial Hospital
- Target Recruit Count
- 240
- Registration Number
- NCT03383003
- Locations
- šØš³
Wei-Chen Tai, Kaohsiung, Taiwan
Pharmacokinetics and Safety Studies of Esomeprazole Use in Schizophrenia Patients
- First Posted Date
- 2017-11-07
- Last Posted Date
- 2018-03-29
- Lead Sponsor
- National Taiwan University Hospital
- Target Recruit Count
- 25
- Registration Number
- NCT03333603
- Locations
- šØš³
National Taiwan University Hospital Yunlin Branch, Taipei, Taiwan
šØš³National Taiwan University Hospital, Taipei, Taiwan
The Effect of Broccoli Sprout Extract and Probiotics for Eradication of Helicobacter Pylori
- First Posted Date
- 2017-07-18
- Last Posted Date
- 2019-06-04
- Lead Sponsor
- Kyunghee University Medical Center
- Target Recruit Count
- 360
- Registration Number
- NCT03220542
- Locations
- š°š·
Kyung Hee University Hospital, Seoul, Korea, Republic of
A Study to Compare PK, PD and Safety of CKD-381 in Healthy Subjects
- First Posted Date
- 2017-07-07
- Last Posted Date
- 2017-11-21
- Lead Sponsor
- Chong Kun Dang Pharmaceutical
- Target Recruit Count
- 41
- Registration Number
- NCT03211143
- Locations
- š°š·
Severance Hospital, Seoul, Korea, Republic of
Study to Evaluate the Efficacy and Safety of DWP14012 in Patients With Erosive Gastroesophageal Reflux Disease (Phase 2, Therapeutic Exploratory Study)
- Conditions
- Interventions
- First Posted Date
- 2017-06-12
- Last Posted Date
- 2020-09-03
- Lead Sponsor
- Daewoong Pharmaceutical Co. LTD.
- Target Recruit Count
- 211
- Registration Number
- NCT03184324
- Locations
- š°š·
Hanyang University Medical Center, Sungdong-gu, Seoul, Korea, Republic of
Effect of Vitamin D on Drug Resistant Helicobacter Pylori (HP) Eradication Study
- First Posted Date
- 2017-05-05
- Last Posted Date
- 2017-05-05
- Lead Sponsor
- Chinese University of Hong Kong
- Target Recruit Count
- 96
- Registration Number
- NCT03142620
- Locations
- šš°
Prince of Wales Hospital, Hong Kong, Hong Kong
A Study to Evaluate the Effects of Food and Esomeprazole on the Pharmacokinetics of Crizotinib in a Coated Microsphere Formulation.
- First Posted Date
- 2017-05-02
- Last Posted Date
- 2017-10-31
- Lead Sponsor
- Pfizer
- Target Recruit Count
- 18
- Registration Number
- NCT03137134
- Locations
- šŗšø
Pfizer New Haven Clinical Research Unit, New Haven, Connecticut, United States
Drug-drug Interaction Between Aceclofenac 200 mg and Esomeprazole 20 mg in Healthy Male Volunteers
- Conditions
- Interventions
- First Posted Date
- 2017-04-25
- Last Posted Date
- 2017-04-25
- Lead Sponsor
- Dong Wha Pharmaceutical Co. Ltd.
- Target Recruit Count
- 30
- Registration Number
- NCT03127046
- Locations
- š°š·
Chonbuk National University Hospital., Jeonju-si, Jeollabuk-do, Korea, Republic of
10-day Versus 14-day Concomitant PAMC as First-line Treatment Strategy for the Eradication of H. Pylori Infection
- First Posted Date
- 2016-11-09
- Last Posted Date
- 2018-03-29
- Lead Sponsor
- Elpen Pharmaceutical Co. Inc.
- Target Recruit Count
- 364
- Registration Number
- NCT02959255
- Locations
- š¬š·
Army Hospital, Athens, Greece
Drug Development Updates
Stay informed with timely notifications on clinical trials, regulatory changes, and research advancements related to this medication.