Leuprolide
- Generic Name
- Leuprolide
- Brand Names
- Camcevi, Eligard, Fensolvi, Lupaneta Pack 1-month, Lupron, Lupron Depot-ped, Viadur, Zeulide Depot
- Drug Type
- Small Molecule
- Chemical Formula
- C59H84N16O12
- CAS Number
- 53714-56-0
- Unique Ingredient Identifier
- EFY6W0M8TG
- Background
Leuprolide is a synthetic 9-residue peptide analogue of gonadotropin-releasing hormone (GnRH). Unlike the endogenous decapeptide GnRH, leuprolide contains a single D-amino acid (D-leucyl) residue, which helps to increase its circulating half-life from three to four minutes to approximately three hours. As a GnRH mimic, leuprolide is capable of binding to the...
- Indication
Leuprolide is indicated for the treatment of advanced prostate cancer and as palliative treatment of advanced prostate cancer.
It is also used for the treatment of pediatric patients with central precocious puberty (CPP).
...
- Associated Conditions
- Advanced Prostate Cancer, Anemia, Central Precocious Puberty (CPP), Endometriosis
- Associated Therapies
- Palliative Treatment
Phase II Study of Leuprolide and Testosterone for Men With Kennedy's Disease or Other Motor Neuron Disease
- Conditions
- First Posted Date
- 2000-02-25
- Last Posted Date
- 2005-06-24
- Lead Sponsor
- National Center for Research Resources (NCRR)
- Target Recruit Count
- 40
- Registration Number
- NCT00004771
A Treatment Study for Premenstrual Syndrome (PMS)
- First Posted Date
- 1999-11-04
- Last Posted Date
- 2023-03-02
- Lead Sponsor
- National Institute of Mental Health (NIMH)
- Target Recruit Count
- 60
- Registration Number
- NCT00001259
- Locations
- 🇺🇸
National Institutes of Health Clinical Center, 9000 Rockville Pike, Bethesda, Maryland, United States
Purification of Testis-Stimulating Factor in Precocious Puberty
- Conditions
- First Posted Date
- 1999-10-19
- Last Posted Date
- 2005-06-24
- Lead Sponsor
- National Center for Research Resources (NCRR)
- Target Recruit Count
- 4
- Registration Number
- NCT00004344
Leuprolide in Treating Adults With Hypogonadotropism
- Conditions
- First Posted Date
- 1999-10-19
- Last Posted Date
- 2015-03-25
- Lead Sponsor
- University of Chicago
- Target Recruit Count
- 45
- Registration Number
- NCT00004438
- Locations
- 🇺🇸
University of Chicago Children's Hospital, Chicago, Illinois, United States
Randomized Study of Hormonal Regulation of Infantile Hemangioma
- Conditions
- First Posted Date
- 1999-10-19
- Last Posted Date
- 2015-03-25
- Lead Sponsor
- FDA Office of Orphan Products Development
- Target Recruit Count
- 30
- Registration Number
- NCT00004436
Leuprolide in Determining the Cause of Gonadotropin Deficiency
- Conditions
- First Posted Date
- 1999-10-19
- Last Posted Date
- 2015-03-26
- Lead Sponsor
- University of Chicago
- Target Recruit Count
- 90
- Registration Number
- NCT00004426
- Locations
- 🇺🇸
University of Chicago Children's Hospital, Chicago, Illinois, United States
Drug Development Updates
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