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Travoprost

Generic Name
Travoprost
Brand Names
Duotrav, Izba, Travatan
Drug Type
Small Molecule
Chemical Formula
C26H35F3O6
CAS Number
157283-68-6
Unique Ingredient Identifier
WJ68R08KX9

Overview

Travoprost ophthalmic solution is a topical medication used for controlling the progression of glaucoma or ocular hypertension, by reducing intraocular pressure . It is a synthetic prostaglandin F2alpha analog . Having been a well-received therapeutic agent with demonstrated efficacy and safety, travoprost is currently approved by the US FDA as a first-line treatment for lowering intraocular pressure in patients with open-angle glaucoma or ocular hypotension . Furthermore, this approval also solidifies the medication as the first and only prostaglandin analog approved by the FDA for first-line treatment of glaucoma patients that does not contain the preservative benzalkonium chloride . Moreover, travoprost is also currently approved in the EU for the decrease of elevated intraocular pressure in paediatric patients aged 2 months to < 18 years with ocular hypertension or paediatric glaucoma .

Background

Travoprost ophthalmic solution is a topical medication used for controlling the progression of glaucoma or ocular hypertension, by reducing intraocular pressure . It is a synthetic prostaglandin F2alpha analog . Having been a well-received therapeutic agent with demonstrated efficacy and safety, travoprost is currently approved by the US FDA as a first-line treatment for lowering intraocular pressure in patients with open-angle glaucoma or ocular hypotension . Furthermore, this approval also solidifies the medication as the first and only prostaglandin analog approved by the FDA for first-line treatment of glaucoma patients that does not contain the preservative benzalkonium chloride . Moreover, travoprost is also currently approved in the EU for the decrease of elevated intraocular pressure in paediatric patients aged 2 months to < 18 years with ocular hypertension or paediatric glaucoma .

Indication

Travoprost ophthalmic solution is indicated for the reduction of elevated intraocular pressure in patients with open-angle glaucoma or ocular hypertension . Travoprost is also currently indicated for the decrease of elevated intraocular pressure in paediatric patients aged 2 months to < 18 years with ocular hypertension or paediatric glaucoma .

Associated Conditions

  • Increased Intra Ocular Pressure (IOP)

FDA Approved Products

Travoprost Ophthalmic Solution
Manufacturer:Bryant Ranch Prepack
Route:OPHTHALMIC
Strength:0.04 mg in 1 mL
Approved: 2021/09/15
NDC:63629-8839
Travoprost Ophthalmic Solution USP, 0.004% Travoprost
Manufacturer:Alembic Pharmaceuticals Inc.
Route:OPHTHALMIC
Strength:0.04 mg in 1 mL
Approved: 2019/12/20
NDC:62332-510
Travoprost Ophthalmic Solution
Manufacturer:Bryant Ranch Prepack
Route:OPHTHALMIC
Strength:0.04 mg in 1 mL
Approved: 2021/09/15
NDC:63629-8840
Travoprost Ophthalmic Solution, 0.004%
Manufacturer:Mylan Pharmaceuticals Inc.
Route:OPHTHALMIC
Strength:0.04 mg in 1 mL
Approved: 2020/01/14
NDC:0378-9651
Travoprost
Manufacturer:Apotex Corp.
Route:OPHTHALMIC
Strength:0.04 mg in 1 mL
Approved: 2023/12/05
NDC:60505-0593

Singapore Approved Products

TRAVOPROST PH&T EYE DROPS SOLUTION 40MCG/ML
Manufacturer:RAFARM S.A.
Form:SOLUTION, STERILE
Strength:0.040 mg/ml
Online:Yes
Approved: 2017/07/26
Approval:SIN15305P
TRAVATAN C EYE DROP SOLUTION 30MCG/ML
Manufacturer:S.A. Alcon-Couvreur N.V., Alcon Laboratories Inc - ASPEX
Form:SOLUTION, STERILE
Strength:0.03 mg/ml
Online:Yes
Approved: 2017/04/10
Approval:SIN15206P
TRAVON EYE DROPS SOLUTION 0.004%
Manufacturer:Indoco Remedies Limited
Form:SOLUTION, STERILE
Strength:0.04mg/ ml
Online:Yes
Approved: 2018/03/09
Approval:SIN15446P
DuoTrav Eye Drops, Solution (5mg/40mcg) per mL
Manufacturer:Alcon-Couvreur NV, ALCON SINGAPORE MANUFACTURING PTE. LTD.
Form:SOLUTION, STERILE
Strength:40 ug/ml
Online:Yes
Approved: 2009/11/03
Approval:SIN13722P

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