Ketoprofen

Generic Name: Ketoprofen

Brand Names: -

Drug Type: Small Molecule

Chemical Formula: C_₁₆H_₁₄O_₃

CAS Number: 22071-15-4

Unique Ingredient Identifier: 90Y4QC304K

Background: Ketoprofen, a propionic acid derivative, is a nonsteroidal anti-inflammatory agent (NSAIA) with analgesic and antipyretic properties.

Indication: For symptomatic treatment of acute and chronic rheumatoid arthritis, osteoarthritis, ankylosing spondylitis, primary dysmenorrhea and mild to moderate pain associated with musculotendinous trauma (sprains and strains), postoperative (including dental surgery) or postpartum pain.

Associated Conditions: Ankylosing Spondylitis (AS), Migraine, Mild pain, Osteoarthritis (OA), Post Partum Pain, Postoperative pain, Primary Dysmenorrhoea, Rheumatoid Arthritis, Moderate Pain

Associated Therapies: -

Clinical Trials

Reduce Nonsteroidal Antiinflammatory Drugs Doses for Analgesia After Sternotomy

Phase 2

Conditions: Cardiac Surgery
Post-operative Pain

Interventions: Drug: Ketoprofen

First Posted Date: 2014-07-02

Last Posted Date: 2014-07-02

Lead Sponsor: University Hospital, Clermont-Ferrand

Target Recruit Count: 100

Registration Number: NCT02180087

Locations: 🇫🇷
CHU de Clermont-Ferrand, Clermont-Ferrand, France

Novel Topical Therapies for the Treatment of Genital Pain

Phase 2

Completed

Conditions: Female Genital Diseases

Interventions: Drug: placebo
Drug: Amitriptyline
Drug: Baclofen
Drug: Ketoprofen
Drug: Ketamine
Drug: Loperamide
Drug: Gabapentin

First Posted Date: 2014-03-28

Last Posted Date: 2016-07-15

Lead Sponsor: University of Rochester

Target Recruit Count: 9

Registration Number: NCT02099006

Locations: 🇺🇸
University of Rochester, Rochester, New York, United States

Non-opioid Analgesic Combination With Morphine for Postoperative Analgesia.

Phase 4

Terminated

Conditions: Post Operative Analgesia

Interventions: Drug: Paracetamol
Drug: Nefopam
Drug: Ketoprofen
Drug: Morphine

First Posted Date: 2013-06-20

Last Posted Date: 2018-02-06

Lead Sponsor: Rennes University Hospital

Target Recruit Count: 223

Registration Number: NCT01882530

Locations: 🇫🇷
Marcel Chauvin, Boulogne, France
🇫🇷
Xavier Capdevila, Montpellier, France
🇫🇷
Hawa Keita-Meyer, Colombes, France

and more 16 locations

Safety and Efficacy of Nonsteroidal Antiinflammatory (NSAI)Drug and Glucocorticoids in Acute Sciatica

Phase 4

Completed

Conditions: Sciatica

Interventions: Drug: methylprednisolone
Drug: Ketoprofen
Drug: Sodium Chloride

First Posted Date: 2013-03-22

Last Posted Date: 2016-03-24

Lead Sponsor: University Hospital, Grenoble

Target Recruit Count: 50

Registration Number: NCT01816334

Locations: 🇫🇷
CH d'Uriage, Uriage, France
🇫🇷
CHU Hôpital Sud, Echirolles, France

Study to Assess the Efficacy and Safety of Ibuprofen 50 mg/g Gel Compared to Profenid 25mg/g Gel

Phase 3

Conditions: Muscular Atrophy
Sprains
Tendonitis

Interventions: Drug: Profenid
Drug: Ibuprofen

First Posted Date: 2011-06-15

Last Posted Date: 2011-06-15

Lead Sponsor: Laboratório Teuto Brasileiro S/A

Target Recruit Count: 144

Registration Number: NCT01373697

Locations: 🇧🇷
ABC School of Medicine, São Paulo, Brazil

Study of Epicutaneously Applied Ketoprofen Transfersome® Gel With or Without Combination With Oral Celecoxib for the Treatment of Muscle Pain Induced by Eccentric Exercise

Phase 1

Completed

Conditions: Musculoskeletal Pain

Interventions: Drug: Celecoxib, Ketoprofen
Drug: Ketoprofen

First Posted Date: 2009-11-25

Last Posted Date: 2010-06-28

Lead Sponsor: X-pert Med GmbH

Target Recruit Count: 82

Registration Number: NCT01020279

Locations: 🇩🇪
X-pert Med GmbH, Jena, Germany

Study of Non Inferiority Bi-Profenid® 200mg Versus Bi-Profenid® 300mg Among Patients Presenting of the Post-traumatic or Rheumatologic Acute Affections of the Locomotor Apparatus (BIPROPAIN)

Phase 3

Completed

Conditions: Pain

Interventions: Drug: ketoprofen 100 mg
Drug: ketoprofen

First Posted Date: 2008-12-17

Last Posted Date: 2009-09-25

Lead Sponsor: Sanofi

Target Recruit Count: 409

Registration Number: NCT00810121

Locations: 🇫🇷
Sanofi-Aventis Administrative Office, Paris, France

Evaluation of Inflammatory Symptoms Reduction With Amoxicillin + Ketoprofen in Acute Pharyngeal Tonsillitis in Pediatric Patients

Phase 4

Terminated

Conditions: Pharyngotonsillitis

Interventions: Drug: Ketoprofen
Drug: Placebo (for Ketoprofen)
Drug: Amoxicillin

First Posted Date: 2008-12-01

Last Posted Date: 2014-10-24

Lead Sponsor: Sanofi

Target Recruit Count: 106

Registration Number: NCT00799838

Locations: 🇧🇷
Sanofi-Aventis Administrative Office, Sao Paulo, Brazil

Trial on Metoclopramide and Ketoprofen in Acute Migraine of Childhood

Phase 3

Withdrawn

Conditions: Migraine

Interventions: Drug: metoclopramide
Drug: ketoprofen
Drug: placebo

First Posted Date: 2007-11-14

Last Posted Date: 2017-08-24

Lead Sponsor: IRCCS Burlo Garofolo

Registration Number: NCT00557544

Locations: 🇮🇹
Edoardo Guglia, Trieste, Italy

A Long-Term Safety Study of IDEA-033 in Comparison to Oral Naproxen for the Treatment of Osteoarthritis of the Knee

Phase 2

Completed

Conditions: Osteoarthritis, Knee

First Posted Date: 2005-12-14

Last Posted Date: 2009-03-20

Lead Sponsor: IDEA AG

Target Recruit Count: 550

Registration Number: NCT00265304

Locations: 🇺🇸
Community Research Managment Associates, Cincinatti, Ohio, United States
🇺🇸
Gilbert Medical Research, Bethany, Oklahoma, United States
🇺🇸
Radiant Research-daytona, Daytona Beach, Florida, United States

and more 3 locations

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