MedPath

PYX-201

Generic Name
PYX-201
Brand Names
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Drug Type
Biotech
Chemical Formula
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CAS Number
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Unique Ingredient Identifier
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Background

PYX-201 is an antibody-drug conjugate directed against the extra domain-B splice variant of fibronectin.

Associated Conditions
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Associated Therapies
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Pyxis Oncology price target lowered to $5 from $7 at H.C. Wainwright

H.C. Wainwright reduces Pyxis Oncology's (PYXS) price target to $5 from $7, maintaining a Buy rating. Pyxis shifts focus from PYX-106 to PYX-201, its lead antibody-drug conjugate, due to Siglec-15's questionable potential, aiding in operational expense management and PYX-201 development focus.

Pyxis Oncology Announces Portfolio Prioritization, Focusing Resources on its Lead Clinical Program, PYX-201

Pyxis Oncology prioritizes PYX-201, a novel ADC showing promise in HNSCC and other solid tumors, with a 50% ORR in HNSCC patients. Current funding supports development into 2H 2026. PYX-106 deprioritized to focus resources on PYX-201, with trials expected to begin in early 2025.
investing.com
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Pyxis Oncology's SWOT analysis: ADC developer's stock shows promise amid trials

Pyxis Oncology, focused on ADCs for cancer treatment, has a strong liquidity position and is progressing with its lead candidate, PYX-201, showing efficacy across six tumor types. The company's market cap is $96.33M, with analyst targets ranging from $7 to $13. Success of PYX-201 could double the share price, but safety concerns and competitive ADC landscape pose risks.
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