Lactulose

Generic Name
Lactulose
Brand Names
Constulose, Enulose, Generlac, Kristalose
Drug Type
Small Molecule
Chemical Formula
C12H22O11
CAS Number
4618-18-2
Unique Ingredient Identifier
9XH2P2N8EP
Background

Lactulose is a synthetic disaccharide derivative of lactose that is most commonly used as a laxative agent despite also being formally indicated to serve as an adjunct therapy in treating portal-systemic encephalopathy (PSE). Despite being first synthesized in 1929, investigations regarding its possible use as a laxative for the treatment of chronic constipa...

Indication

Lactulose is indicated for use as a laxative in the treatment of chronic constipation in adults and geriatric patients.
...

Associated Conditions
Constipation, Hepatic Encephalopathy (HE)
Associated Therapies
-

Lactulose for the Prevention of Nosocomial Infections in Children

Not Applicable
Conditions
First Posted Date
2006-01-10
Last Posted Date
2008-02-06
Lead Sponsor
Bnai Zion Medical Center
Target Recruit Count
100
Registration Number
NCT00273949
Locations
🇮🇱

Pediatric Department, Bnai Zion Medical Center, Haifa, Israel

Trial to Evaluate Effect of Lactulose on Hard Stools in Patients With Hemorrhoids or Anal Fissures

Phase 4
Terminated
Conditions
Interventions
First Posted Date
2005-09-12
Last Posted Date
2008-05-06
Lead Sponsor
Solvay Pharmaceuticals
Target Recruit Count
97
Registration Number
NCT00160290
Locations
🇪🇸

Site 6, Granada, Spain

🇪🇸

Site 2, Barcelona, Spain

🇪🇸

Site 5, Huesca, Spain

and more 5 locations

Phase II Study of Lactulose and Circadian Rhythms in Patients With Cirrhosis

First Posted Date
2000-02-25
Last Posted Date
2005-06-24
Lead Sponsor
National Center for Research Resources (NCRR)
Target Recruit Count
16
Registration Number
NCT00004796
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