MedPath

Tolinapant

Generic Name
Tolinapant
Drug Type
Small Molecule
Chemical Formula
C30H42FN5O3
CAS Number
1799328-86-1
Unique Ingredient Identifier
2LHZ9ZC3YO
Background

ASTX660 is under investigation in clinical trial NCT02503423 (Phase 1-2 Study of ASTX660 in Subjects With Advanced Solid Tumors and Lymphomas).

T-Cell Malignancy Pipeline Shows Promise with Novel Therapies and Approvals

• The T-cell malignancies market is experiencing growth driven by increased incidence, treatment advancements, and strategic biopharma partnerships. • Several companies, including Corvus Pharmaceuticals and Kymera Therapeutics, are advancing novel therapies through clinical trials, targeting unmet needs in T-cell lymphomas. • Regulatory milestones, such as FDA Fast Track Designation for soquelitinib and EMA Orphan Drug Designation for SLS009, are accelerating the development of new treatments. • Research and development efforts, highlighted by presentations at major conferences like EHA, are yielding promising clinical data for drugs like KT-333.
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