Sodium bicarbonate
- Generic Name
- Sodium bicarbonate
- Brand Names
- Alka-seltzer, Alka-seltzer Fruit Chews, Alka-seltzer Heartburn Relief, Bi-peglyte, Bibag, Bicart, Bss Ophthalmic Solution, Ceo-two, Colyte, Gavilyte-C, Gavilyte-G, Gavilyte-H and Bisacodyl, Gavilyte-N, Golytely, H.E.L.P.bicel, Hema Bp-38, Hemacart, Konvomep, Nulytely, Peglyte, Phoxillum, Physioneal 40, Prismasol, Zegerid, Zegerid Reformulated Aug 2006, Zegerid With Magnesium Hydroxide
- Drug Type
- Small Molecule
- Chemical Formula
- CHNaO3
- CAS Number
- 144-55-8
- Unique Ingredient Identifier
- 8MDF5V39QO
- Background
Sodium bicarbonate is a white, crystalline powder that is commonly used as a pH buffering agent, an electrolyte replenisher, systemic alkalizer and in topical cleansing solutions.
- Indication
Sodium bicarbonate is used for the treatment of metabolic acidosis which may occur in severe renal disease, uncontrolled diabetes, circulatory insufficiency due to shock or severe dehydration, extracorporeal circulation of blood, cardiac arrest and severe primary lactic acidosis. Also is indicated in severe diarrhea which is often accompanied by a significan...
- Associated Conditions
- Barbiturate intoxication, Breast Cancer, Constipation, Dental Decay, Duodenal Ulcer, Dyspepsia, Gastro-esophageal Reflux Disease (GERD), Gingival Bleeding, Heartburn, Helicobacter Infections, Hyperkalemia, Ischaemia, Metabolic Acidosis, Myocardial Infarction, Plaque, Dental, Pruritis of the skin, Skin Irritation, Upper GI Bleeding, Upset stomach, Zollinger-Ellison Syndrome, Abdominal bloating, Benign, active Gastric Ulcer, Methyl alcohol poisoning, Prophylaxis of Contrast-induced nephropathy, Salicylate poisoning, Severe Diarrhea, Swelling of the gums
- Associated Therapies
- Bowel preparation therapy
Laser Ablation Versus Mechanochemical Ablation Trial
- Conditions
- Interventions
- First Posted Date
- 2015-12-11
- Last Posted Date
- 2023-09-21
- Lead Sponsor
- Hull University Teaching Hospitals NHS Trust
- Target Recruit Count
- 150
- Registration Number
- NCT02627846
- Locations
- 🇬🇧
Hull and East Yorkshire Hospitals NHS Trust, Hull, United Kingdom
Extended Use of Sodium Bicarbonate in Patients With Cancer
- First Posted Date
- 2015-08-25
- Last Posted Date
- 2016-04-13
- Lead Sponsor
- University of Arizona
- Target Recruit Count
- 15
- Registration Number
- NCT02531919
- Locations
- 🇺🇸
University of Arizona Medical Center-University Campus, Tucson, Arizona, United States
Effect of Urinary Alkalinization on Urine Uric Acid Precipitation and Crystallization in Adults With Type 1 Diabetes
- Conditions
- Interventions
- First Posted Date
- 2015-07-20
- Last Posted Date
- 2022-01-24
- Lead Sponsor
- University of Colorado, Denver
- Target Recruit Count
- 45
- Registration Number
- NCT02502071
- Locations
- 🇺🇸
Barbara Davis Center for Diabetes, Aurora, Colorado, United States
NAC, NaHCO3 and NS Prophylaxis for CTPA in the ED on Suspicion of PE: A Randomized Controlled Trial
- Conditions
- Interventions
- First Posted Date
- 2015-06-26
- Last Posted Date
- 2015-06-26
- Lead Sponsor
- Karadeniz Technical University
- Target Recruit Count
- 231
- Registration Number
- NCT02483143
- Locations
- 🇹🇷
Karadeniz Technical University Faculty of Medicine, Trabzon, Turkey
Sodium Bicarbonate to Treat Severe Acidosis in the Critically Ill
- First Posted Date
- 2015-06-19
- Last Posted Date
- 2024-05-29
- Lead Sponsor
- University Hospital, Montpellier
- Target Recruit Count
- 400
- Registration Number
- NCT02476253
- Locations
- 🇫🇷
DAR St Eloi, Montpellier, France
Acid-Base Compensation in Chronic Kidney Disease
- Conditions
- Interventions
- First Posted Date
- 2015-04-28
- Last Posted Date
- 2017-08-30
- Lead Sponsor
- Duke University
- Target Recruit Count
- 14
- Registration Number
- NCT02427594
- Locations
- 🇺🇸
Duke University School of Medicine, Durham, North Carolina, United States
Sympatholysis in Chronic Kidney Disease
- Conditions
- Interventions
- First Posted Date
- 2015-04-08
- Last Posted Date
- 2023-09-13
- Lead Sponsor
- Emory University
- Target Recruit Count
- 110
- Registration Number
- NCT02411773
- Locations
- 🇺🇸
Atlanta VA Medical Center, Decatur, Georgia, United States
Bicarbonate in Patients With Out-of-hospital Cardiac Arrest
- Conditions
- Interventions
- First Posted Date
- 2014-12-01
- Last Posted Date
- 2022-03-25
- Lead Sponsor
- Asan Medical Center
- Target Recruit Count
- 50
- Registration Number
- NCT02303548
Effect of Sodium Bicarbonate Buffered Lidocaine on the Success of IAN Block of Teeth With Irreversible Pulpitis
- First Posted Date
- 2014-08-27
- Last Posted Date
- 2016-08-31
- Lead Sponsor
- Masoud Saatchi
- Target Recruit Count
- 80
- Registration Number
- NCT02226913
Sodium Bicarbonate to Prevent Acute Kidney Injury in Children Undergoing Cardiac Surgery
- Conditions
- Interventions
- First Posted Date
- 2014-01-27
- Last Posted Date
- 2022-11-02
- Lead Sponsor
- Northwell Health
- Target Recruit Count
- 51
- Registration Number
- NCT02046135
- Locations
- 🇺🇸
Cohen Children's Medical Center of New York, New Hyde Park, New York, United States
Drug Development Updates
Stay informed with timely notifications on clinical trials, regulatory changes, and research advancements related to this medication.