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Sodium bicarbonate

Generic Name
Sodium bicarbonate
Brand Names
Alka-seltzer, Alka-seltzer Fruit Chews, Alka-seltzer Heartburn Relief, Bi-peglyte, Bibag, Bicart, Bss Ophthalmic Solution, Ceo-two, Colyte, Gavilyte-C, Gavilyte-G, Gavilyte-H and Bisacodyl, Gavilyte-N, Golytely, H.E.L.P.bicel, Hema Bp-38, Hemacart, Konvomep, Nulytely, Peglyte, Phoxillum, Physioneal 40, Prismasol, Zegerid, Zegerid Reformulated Aug 2006, Zegerid With Magnesium Hydroxide
Drug Type
Small Molecule
Chemical Formula
CHNaO3
CAS Number
144-55-8
Unique Ingredient Identifier
8MDF5V39QO

Overview

Sodium bicarbonate is a white, crystalline powder that is commonly used as a pH buffering agent, an electrolyte replenisher, systemic alkalizer and in topical cleansing solutions.

Background

Sodium bicarbonate is a white, crystalline powder that is commonly used as a pH buffering agent, an electrolyte replenisher, systemic alkalizer and in topical cleansing solutions.

Indication

Sodium bicarbonate is used for the treatment of metabolic acidosis which may occur in severe renal disease, uncontrolled diabetes, circulatory insufficiency due to shock or severe dehydration, extracorporeal circulation of blood, cardiac arrest and severe primary lactic acidosis. Also is indicated in severe diarrhea which is often accompanied by a significant loss of bicarbonate. Further indicated in the treatment of certain drug intoxications, including barbiturates (where dissociation of the barbiturateprotein complex is desired), in poisoning by salicylates or methyl alcohol and in hemolytic reactions requiring alkalinization of the urine to diminish nephrotoxicity of blood pigments.

Associated Conditions

  • Barbiturate intoxication
  • Breast Cancer
  • Constipation
  • Dental Decay
  • Duodenal Ulcer
  • Dyspepsia
  • Gastro-esophageal Reflux Disease (GERD)
  • Gingival Bleeding
  • Heartburn
  • Helicobacter Infections
  • Hyperkalemia
  • Ischaemia
  • Metabolic Acidosis
  • Myocardial Infarction
  • Plaque, Dental
  • Pruritis of the skin
  • Skin Irritation
  • Upper GI Bleeding
  • Upset stomach
  • Zollinger-Ellison Syndrome
  • Abdominal bloating
  • Benign, active Gastric Ulcer
  • Methyl alcohol poisoning
  • Prophylaxis of Contrast-induced nephropathy
  • Salicylate poisoning
  • Severe Diarrhea
  • Swelling of the gums

FDA Approved Products

Sodium Bicarbonate
Manufacturer:A-S Medication Solutions
Route:INTRAVENOUS
Strength:84 mg in 1 mL
Approved: 2021/03/03
NDC:50090-0530
PRISMASOL BGK2/3.5
Manufacturer:Baxter Healthcare Corporation
Route:INTRAVENOUS
Strength:3.09 g in 1 L
Approved: 2018/11/01
NDC:24571-103
PHOXILLUM B22K4/0
Manufacturer:Baxter Healthcare Corporation
Route:INTRAVENOUS
Strength:2.21 g in 1 L
Approved: 2018/11/01
NDC:24571-117
Sodium Bicarbonate
Manufacturer:OMNIVIUM PHARMACEUTICALS LLC.
Route:INTRAVENOUS
Strength:84 mg in 1 mL
Approved: 2023/08/14
NDC:81665-200
SODIUM BICARBONATE
Manufacturer:Hospira, Inc.
Route:INTRAVENOUS
Strength:84 mg in 1 mL
Approved: 2021/03/03
NDC:0409-6625

Singapore Approved Products

GAVISCON LIQUID SACHETS
Manufacturer:RECKITT BENCKISER HEALTHCARE (UK) LIMITED
Form:SUSPENSION
Strength:267MG/10ML
Online:Yes
Approved: 2009/11/23
Approval:SIN13738P
E-Z-GAS II GRANULES
Manufacturer:Tower Laboratories
Form:GRANULE
Strength:2.22 g/4 g
Online:Yes
Approved: 1991/07/11
Approval:SIN06442P
DUOSOL WITH 4 MMOL/L POTASSIUM SOLUTION FOR HAEMOFILTRATION
Manufacturer:B. Braun Avitum AG
Form:SOLUTION, STERILE
Strength:3.59g/1000ml
Online:Yes
Approved: 2019/08/20
Approval:SIN15785P
INON GRANULES
Manufacturer:SATO PHARMACEUTICAL CO LTD
Form:GRANULE
Strength:525 mg/1.8 g
Online:Yes
Approved: 1989/06/08
Approval:SIN03440P
GAVISCON PEPPERMINT TABLETS
Manufacturer:RECKITT BENCKISER HEALTHCARE (UK) LIMITED
Form:TABLET, CHEWABLE
Strength:133.5MG
Online:Yes
Approved: 2011/04/14
Approval:SIN13947P

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