Sodium bicarbonate
- Generic Name
- Sodium bicarbonate
- Brand Names
- Alka-seltzer, Alka-seltzer Fruit Chews, Alka-seltzer Heartburn Relief, Bi-peglyte, Bibag, Bicart, Bss Ophthalmic Solution, Ceo-two, Colyte, Gavilyte-C, Gavilyte-G, Gavilyte-H and Bisacodyl, Gavilyte-N, Golytely, H.E.L.P.bicel, Hema Bp-38, Hemacart, Konvomep, Nulytely, Peglyte, Phoxillum, Physioneal 40, Prismasol, Zegerid, Zegerid Reformulated Aug 2006, Zegerid With Magnesium Hydroxide
- Drug Type
- Small Molecule
- Chemical Formula
- CHNaO3
- CAS Number
- 144-55-8
- Unique Ingredient Identifier
- 8MDF5V39QO
- Background
Sodium bicarbonate is a white, crystalline powder that is commonly used as a pH buffering agent, an electrolyte replenisher, systemic alkalizer and in topical cleansing solutions.
- Indication
Sodium bicarbonate is used for the treatment of metabolic acidosis which may occur in severe renal disease, uncontrolled diabetes, circulatory insufficiency due to shock or severe dehydration, extracorporeal circulation of blood, cardiac arrest and severe primary lactic acidosis. Also is indicated in severe diarrhea which is often accompanied by a significan...
- Associated Conditions
- Barbiturate intoxication, Breast Cancer, Constipation, Dental Decay, Duodenal Ulcer, Dyspepsia, Gastro-esophageal Reflux Disease (GERD), Gingival Bleeding, Heartburn, Helicobacter Infections, Hyperkalemia, Ischaemia, Metabolic Acidosis, Myocardial Infarction, Plaque, Dental, Pruritis of the skin, Skin Irritation, Upper GI Bleeding, Upset stomach, Zollinger-Ellison Syndrome, Abdominal bloating, Benign, active Gastric Ulcer, Methyl alcohol poisoning, Prophylaxis of Contrast-induced nephropathy, Salicylate poisoning, Severe Diarrhea, Swelling of the gums
- Associated Therapies
- Bowel preparation therapy
The Effects of Urinary pH Changes on an Investigational Compound in Healthy Subjects
- Conditions
- Interventions
- First Posted Date
- 2011-09-26
- Last Posted Date
- 2011-10-12
- Lead Sponsor
- Eli Lilly and Company
- Target Recruit Count
- 30
- Registration Number
- NCT01440478
- Locations
- 🇬🇧
For additional information regarding investigative sites for this trial, contact 1-877-CTLILLY (1-877-285-4559, 1-317-615-4559), Mon - Fri, from 9 AM to 5 PM Eastern Time (UTC/GMT - 5 hours, EST) or speak with your personal physician., Leeds, United Kingdom
Sodium Bicarbonate in Cardiopulmonary Resuscitation
- First Posted Date
- 2011-06-21
- Last Posted Date
- 2011-11-08
- Lead Sponsor
- Rambam Health Care Campus
- Target Recruit Count
- 2130
- Registration Number
- NCT01377337
- Locations
- 🇮🇱
Rambam Medical Center, Haifa, Israel
🇮🇱Magen David Adom, Tel Aviv, Israel
Blood Gas Analysis and Buffering In Cardiac Arrest
- Conditions
- Interventions
- First Posted Date
- 2011-05-30
- Last Posted Date
- 2014-06-03
- Lead Sponsor
- Medical University of Graz
- Target Recruit Count
- 700
- Registration Number
- NCT01362556
- Locations
- 🇦🇹
LKH Graz West, Graz, Styria, Austria
🇦🇹Landeskrankenhaus Klagenfurt, Klagenfurt, Carinthia, Austria
🇦🇹Landesklinikum Wiener Neustadt, Wiener Neustadt, Lower Austria, Austria
Study of Sodium Bicarbonate in Kidney Transplant Recipients
- First Posted Date
- 2010-10-21
- Last Posted Date
- 2016-04-06
- Lead Sponsor
- University of Utah
- Target Recruit Count
- 29
- Registration Number
- NCT01225796
- Locations
- 🇺🇸
University of Utah, Salt Lake City, Utah, United States
Intravenous Sodium Bicarbonate Verifies Intravenous Position of Catheters in Anesthetized Children
- First Posted Date
- 2010-10-13
- Last Posted Date
- 2010-10-28
- Lead Sponsor
- Sheba Medical Center
- Target Recruit Count
- 30
- Registration Number
- NCT01219322
- Locations
- 🇮🇱
Sheba Medical Center, Tel Hashomer, Israel
Sodium Bicarbonate for Prevention of Contrast-Induced Nephropathy
- First Posted Date
- 2010-07-29
- Last Posted Date
- 2014-02-19
- Lead Sponsor
- Hospital Sao Lucas da PUCRS
- Target Recruit Count
- 301
- Registration Number
- NCT01172353
- Locations
- 🇧🇷
São Lucas Hospital - PUCRS University, Porto Alegre, RS, Brazil
Prevention of Contrast-induced Nephropathy in Patients With Acute Myocardial Infarction
- Conditions
- Interventions
- First Posted Date
- 2010-07-12
- Last Posted Date
- 2013-03-22
- Lead Sponsor
- Odense University Hospital
- Target Recruit Count
- 720
- Registration Number
- NCT01160627
- Locations
- 🇩🇰
Odense University Hospital, Odense, Denmark
Pharmacodynamic Study Comparing the Effects of Two Different Forms of Omeprazole (P07812) (COMPLETED)
- Conditions
- Interventions
- First Posted Date
- 2010-02-26
- Last Posted Date
- 2015-03-11
- Lead Sponsor
- Bayer
- Target Recruit Count
- 30
- Registration Number
- NCT01077076
Study to Compare Gastric Inhibition of Two Proton Pump Inhibitors (CL2008-18)(P07815)(COMPLETED)
- First Posted Date
- 2009-11-01
- Last Posted Date
- 2015-03-11
- Lead Sponsor
- Bayer
- Target Recruit Count
- 63
- Registration Number
- NCT01005719
Prevention of Contrast-Induced Nephropathy in Diabetic Patients With Undergoing Coronary Angiography
- First Posted Date
- 2009-07-31
- Last Posted Date
- 2009-07-31
- Lead Sponsor
- CardioVascular Research Foundation, Korea
- Target Recruit Count
- 368
- Registration Number
- NCT00950079
- Locations
- 🇰🇷
Asan Medical Center, Seoul, Korea, Republic of
🇰🇷Busan Saint Mary Hospital, Busan, Korea, Republic of
🇰🇷Chungnam National University Hospital, Daejeon, Korea, Republic of
Drug Development Updates
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