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Sodium bicarbonate

Generic Name
Sodium bicarbonate
Brand Names
Alka-seltzer, Alka-seltzer Fruit Chews, Alka-seltzer Heartburn Relief, Bi-peglyte, Bibag, Bicart, Bss Ophthalmic Solution, Ceo-two, Colyte, Gavilyte-C, Gavilyte-G, Gavilyte-H and Bisacodyl, Gavilyte-N, Golytely, H.E.L.P.bicel, Hema Bp-38, Hemacart, Konvomep, Nulytely, Peglyte, Phoxillum, Physioneal 40, Prismasol, Zegerid, Zegerid Reformulated Aug 2006, Zegerid With Magnesium Hydroxide
Drug Type
Small Molecule
Chemical Formula
CHNaO3
CAS Number
144-55-8
Unique Ingredient Identifier
8MDF5V39QO

Overview

Sodium bicarbonate is a white, crystalline powder that is commonly used as a pH buffering agent, an electrolyte replenisher, systemic alkalizer and in topical cleansing solutions.

Background

Sodium bicarbonate is a white, crystalline powder that is commonly used as a pH buffering agent, an electrolyte replenisher, systemic alkalizer and in topical cleansing solutions.

Indication

Sodium bicarbonate is used for the treatment of metabolic acidosis which may occur in severe renal disease, uncontrolled diabetes, circulatory insufficiency due to shock or severe dehydration, extracorporeal circulation of blood, cardiac arrest and severe primary lactic acidosis. Also is indicated in severe diarrhea which is often accompanied by a significant loss of bicarbonate. Further indicated in the treatment of certain drug intoxications, including barbiturates (where dissociation of the barbiturateprotein complex is desired), in poisoning by salicylates or methyl alcohol and in hemolytic reactions requiring alkalinization of the urine to diminish nephrotoxicity of blood pigments.

Associated Conditions

  • Barbiturate intoxication
  • Breast Cancer
  • Constipation
  • Dental Decay
  • Duodenal Ulcer
  • Dyspepsia
  • Gastro-esophageal Reflux Disease (GERD)
  • Gingival Bleeding
  • Heartburn
  • Helicobacter Infections
  • Hyperkalemia
  • Ischaemia
  • Metabolic Acidosis
  • Myocardial Infarction
  • Plaque, Dental
  • Pruritis of the skin
  • Skin Irritation
  • Upper GI Bleeding
  • Upset stomach
  • Zollinger-Ellison Syndrome
  • Abdominal bloating
  • Benign, active Gastric Ulcer
  • Methyl alcohol poisoning
  • Prophylaxis of Contrast-induced nephropathy
  • Salicylate poisoning
  • Severe Diarrhea
  • Swelling of the gums

FDA Approved Products

Zegerid
Manufacturer:Physicians Total Care, Inc.
Route:ORAL
Strength:1100 mg in 1 1
Approved: 2012/05/01
NDC:54868-5611
Polyethylene Glycol-3350, Sodium Chloride, Potassium Chloride and Sodium Bicarbonate
Manufacturer:Novel Laboratories, Inc.
Route:ORAL
Strength:5.72 g in 438.4 g
Approved: 2009/11/18
NDC:40032-050
Not Applicable
Manufacturer:Sterling Knight Pharmaceuticals LLC
Route:ORAL
Strength:1100 mg in 1 1
Approved: 2017/07/13
NDC:69336-112
NuLYTELY
Manufacturer:Physicians Total Care, Inc.
Route:ORAL
Strength:2.86 g in 2 L
Approved: 2011/05/11
NDC:54868-4233
Omeprazole, Sodium bicarbonate
Manufacturer:Bryant Ranch Prepack
Route:ORAL
Strength:1100 mg in 1 1
Approved: 2021/06/08
NDC:63629-2491

Singapore Approved Products

PHOXILIUM 1.2 MMOL/L PHOSPHATE SOLUTION FOR HAEMODIALYSIS/HAEMOFILTRATION
Manufacturer:Bieffe Medital S.p.A.
Form:SOLUTION, STERILE
Strength:2.918 g/L
Online:Yes
Approved: 2019/06/27
Approval:SIN15730P
MULTIBIC POTASSIUM-FREE SOLUTION FOR HAEMODIALYSIS/HAEMOFILTRATION
Manufacturer:Fresenius Medical Care Deutschland GmbH
Form:SOLUTION, STERILE
Strength:3.104g/L
Online:Yes
Approved: 2011/12/07
Approval:SIN14061P
PHYSIONEAL 40 DEXTROSE SOLUTION 2.5% w/v/25.0 mg/ml
Manufacturer:BAXTER HEALTHCARE SA, BAXTER HEALTHCARE SA, SINGAPORE BRANCH
Form:SOLUTION, STERILE
Strength:3.29 g/l
Online:Yes
Approved: 2003/10/07
Approval:SIN12436P
MAGTASIL ANTACID MIXTURE
Manufacturer:ICM PHARMA PTE. LTD.
Form:SUSPENSION
Strength:5% w/v
Online:Yes
Approved: 1996/07/03
Approval:SIN08786P
PHYSIONEAL 40 DEXTROSE SOLUTION 1.5% w/v/15.0 mg/ml
Manufacturer:BAXTER HEALTHCARE SA, BAXTER HEALTHCARE SA, SINGAPORE BRANCH
Form:SOLUTION, STERILE
Strength:3.29 g/l
Online:Yes
Approved: 2003/10/07
Approval:SIN12435P

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