Naproxen
- Generic Name
- Naproxen
- Brand Names
- Aleve, Aleve PM, Aleve-D, Anaprox, Naprelan, Naprosyn, Sallus, Sudafed Sinus & Pain, Treximet, Vimovo
- Drug Type
- Small Molecule
- Chemical Formula
- C14H14O3
- CAS Number
- 22204-53-1
- Unique Ingredient Identifier
- 57Y76R9ATQ
- Background
Naproxen is classified as a nonsteroidal anti-inflammatory dug (NSAID) and was initially approved for prescription use in 1976 and then for over-the-counter (OTC) use in 1994. It can effectively manage acute pain as well as pain related to rheumatic diseases, and has a well studied adverse effect profile. Given its overall tolerability and effectiveness, nap...
- Indication
Naproxen is indicated for the management of rheumatoid arthritis, osteoarthritis, ankylosing spondylitis, polyarticular juvenile idiopathic arthritis, tendinitis, bursitis, acute gout, primary dysmenorrhea, and for the relief of mild to moderate pain. Further, it is first-line therapy for osteoarthritis, acute gouty arthritis, dysmenorrhea, and musculoskelet...
- Associated Conditions
- Acute Gouty Arthritis, Acute Migraine, Ankylosing Spondylitis (AS), Back pain, Bursitis, Extra-Articular Rheumatism, Fever, Flu caused by Influenza, Headache, Juvenile Idiopathic Arthritis (JIA), Menstrual Distress (Dysmenorrhea), Migraine, Muscle Spasms, Nasal Congestion, Osteoarthritis (OA), Pain, Post Traumatic Pain, Postoperative pain, Primary Dysmenorrhoea, Rheumatoid Arthritis, Rheumatoid Arthritis, Juvenile, Seasonal Allergic Rhinitis, Sinusitis, Tendinitis, Toothache, Articular inflammation
- Associated Therapies
- -
Randomized Trial of Low-dose Naproxen in Cognitively Intact Persons at Risk of Alzheimer's Dementia
- Conditions
- Interventions
- First Posted Date
- 2016-03-09
- Last Posted Date
- 2017-08-01
- Lead Sponsor
- Douglas Mental Health University Institute
- Target Recruit Count
- 200
- Registration Number
- NCT02702817
- Locations
- 🇨🇦
Douglas Hospital Research Centre, Montreal, Quebec, Canada
Delirium in Elderly Patients With Trauma of the Hip
- First Posted Date
- 2016-02-23
- Last Posted Date
- 2023-08-04
- Target Recruit Count
- 239
- Registration Number
- NCT02689024
- Locations
- 🇳🇱
Meander Medical Center, Amersfoort, Netherlands
🇳🇱VU Medical Center, Amsterdam, Netherlands
🇳🇱Academic Medical Center, Amsterdam, Netherlands
Correlation Between Acute Analgesia and Long-Term Function Following Ankle Injuries
- Conditions
- Interventions
- First Posted Date
- 2016-01-29
- Last Posted Date
- 2024-02-12
- Lead Sponsor
- Canadian Department of National Defense
- Target Recruit Count
- 168
- Registration Number
- NCT02667730
- Locations
- 🇨🇦
2 Fd Amb medical clinic, Petawawa, Ontario, Canada
Orphenadrine and Methocarbamol for LBP
- Conditions
- Interventions
- First Posted Date
- 2016-01-27
- Last Posted Date
- 2018-06-26
- Lead Sponsor
- Montefiore Medical Center
- Target Recruit Count
- 240
- Registration Number
- NCT02665286
- Locations
- 🇺🇸
Montefiore Medical Center, Bronx, New York, United States
Diazepam Use With Standard Management for Acute Low Back Pain
- First Posted Date
- 2016-01-05
- Last Posted Date
- 2018-08-01
- Lead Sponsor
- Montefiore Medical Center
- Target Recruit Count
- 114
- Registration Number
- NCT02646124
- Locations
- 🇺🇸
Montefiore Medical Center, Bronx, New York, United States
A Study to Assess the Analgesic Efficacy of ASP7962 in Patients With Pain Due to Osteoarthritis of the Knee
- Conditions
- Interventions
- First Posted Date
- 2015-11-20
- Last Posted Date
- 2024-10-31
- Lead Sponsor
- Astellas Pharma Europe B.V.
- Target Recruit Count
- 215
- Registration Number
- NCT02611466
- Locations
- 🇭🇺
Site HU36002, Baja, Hungary
🇨🇿Site CZ42006, Hradec Kralove, Czechia
🇧🇪Site BE32003, Leuven, Belgium
Different Analgesics Prior to Intrauterine Device (IUD) Insertion: Is There Any Evidence?
- Conditions
- Interventions
- First Posted Date
- 2015-08-13
- Last Posted Date
- 2016-06-22
- Lead Sponsor
- Al Hayat National Hospital
- Target Recruit Count
- 200
- Registration Number
- NCT02522130
- Locations
- 🇸🇦
Alhayah national hospital, Abha, Saudi Arabia
🇪🇬Menoufia University, Shebin Elkom, Egypt
Copper IUD Treatment Observation Study
- First Posted Date
- 2015-08-10
- Last Posted Date
- 2020-10-14
- Lead Sponsor
- University of Washington
- Target Recruit Count
- 34
- Registration Number
- NCT02519231
- Locations
- 🇺🇸
Harborview Medical Center, Seattle, Washington, United States
🇺🇸John H Stroger Jr Hospital of Cook County, Chicago, Illinois, United States
🇺🇸UW Neighborhood Clinic Northgate, Seattle, Washington, United States
Variability in Response to Non-steroidal Anti-inflammatory Drugs
- First Posted Date
- 2015-07-17
- Last Posted Date
- 2023-12-13
- Lead Sponsor
- University of Pennsylvania
- Target Recruit Count
- 16
- Registration Number
- NCT02502006
- Locations
- 🇺🇸
Institute for Translational Medicine and Therapeutics (ITMAT), University of Pennsylvania School of Medicine, Philadelphia, Pennsylvania, United States
Intensive Urate Lowering Therapy of Febuxostat Compared to Allopurinol on Cardiovascular Risk in Patients With Gout
- Conditions
- Interventions
- First Posted Date
- 2015-07-16
- Last Posted Date
- 2019-06-21
- Lead Sponsor
- Menarini International Operations Luxembourg SA
- Target Recruit Count
- 196
- Registration Number
- NCT02500641
- Locations
- 🇵🇱
Specjalistyczna Praktyka Lekarska Piotr Kubalski, Grudziądz, Poland
🇵🇱Oddział Kardiologiczny, WSS im. W. Biegańskiego w Łodzi, Łódź, Poland
🇷🇴S.C. Cardiomed S.R.L., Craiova, Romania
Drug Development Updates
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