Tryptophan
- Generic Name
- Tryptophan
- Brand Names
- Aminosyn II 7 %, Nephramine, Sulfite-free, Travasol 10, Plenamine, Aminosyn-PF 7%, Hepatamine 8, Clinisol 15, Trophamine 10 %, Clinimix 2.75/5, Freamine III 10, Primene, Prosol, Procalamine 3, Tryptan, Clinimix E 2.75/5, Olimel, Freamine 6.9, Premasol, Periolimel
- Drug Type
- Small Molecule
- Chemical Formula
- C11H12N2O2
- CAS Number
- 73-22-3
- Unique Ingredient Identifier
- 8DUH1N11BX
- Background
An essential amino acid that is necessary for normal growth in infants and for nitrogen balance in adults. It is a precursor of indole alkaloids in plants. It is a precursor of serotonin (hence its use as an antidepressant and sleep aid). It can be a precursor to niacin, albeit inefficiently, in mammals.
- Indication
Tryptophan may be useful in increasing serotonin production, promoting healthy sleep, managing depression by enhancing mental and emotional well-being, managing pain tolerance, and managing weight.
- Associated Conditions
- Renal Failure, Chronic Renal Failure, Depression, Acute Renal Failure (ARF)
- Associated Therapies
- Dialysis therapy, Dietary and Nutritional Therapies, Amino acid supplementation
Tryptophan for Impaired AhR Signaling in Celiac Disease
- Conditions
- Interventions
- First Posted Date
- 2022-10-12
- Last Posted Date
- 2023-10-16
- Lead Sponsor
- McMaster University
- Target Recruit Count
- 50
- Registration Number
- NCT05576038
- Locations
- 🇨🇦
McMaster University, Hamilton, Ontario, Canada
The Effects of Kynurenine Aminotransferase Inhibition in People With Schizophrenia
- Conditions
- Interventions
- First Posted Date
- 2019-07-09
- Last Posted Date
- 2024-11-05
- Lead Sponsor
- University of Maryland, Baltimore
- Target Recruit Count
- 88
- Registration Number
- NCT04013555
- Locations
- 🇺🇸
Maryland Psychiatric Research Center (MPRC) ; the Treatment Research Program (TRP), Catonsville, Maryland, United States
Tryptophan MRI in People With Schizophrenia and Healthy Controls
- First Posted Date
- 2014-02-20
- Last Posted Date
- 2024-07-30
- Lead Sponsor
- University of Maryland, Baltimore
- Target Recruit Count
- 93
- Registration Number
- NCT02067975
- Locations
- 🇺🇸
Maryland Psychiatric Research Center, Catonsville, Maryland, United States
Double Blind Study of Trp01 in Patients With Alzheimer's Disease
- Conditions
- First Posted Date
- 2005-09-20
- Last Posted Date
- 2005-09-20
- Lead Sponsor
- Queen's University
- Target Recruit Count
- 12
- Registration Number
- NCT00202124
- Locations
- 🇨🇦
Queen's University, Kingston, Ontario, Canada
Tryptophan and Behavior Therapy for Cocaine Abuse - 1
- Conditions
- First Posted Date
- 1999-09-21
- Last Posted Date
- 2017-01-12
- Lead Sponsor
- National Institute on Drug Abuse (NIDA)
- Target Recruit Count
- 200
- Registration Number
- NCT00000324
- Locations
- 🇺🇸
Johns Hopkins University School of Medicine, Baltimore, Maryland, United States
Drug Development Updates
Stay informed with timely notifications on clinical trials, regulatory changes, and research advancements related to this medication.