Lorazepam
- Generic Name
- Lorazepam
- Brand Names
- Ativan, Loreev
- Drug Type
- Small Molecule
- Chemical Formula
- C15H10Cl2N2O2
- CAS Number
- 846-49-1
- Unique Ingredient Identifier
- O26FZP769L
- Background
Lorazepam is a short-acting and rapidly cleared benzodiazepine used commonly as a sedative and anxiolytic. It was developed by DJ Richards, presented and marketed initially by Wyeth Pharmaceuticals in the USA in 1977. The first historic FDA label approval is reported in 1985 by the company Mutual Pharm.
- Indication
Lorazepam is FDA-approved for the short-term relief of anxiety symptoms related to anxiety disorders and anxiety associated with depressive symptoms such as anxiety-associated insomnia. It is as well used as an anesthesia premedication in adults to relieve anxiety or to produce sedation/amnesia and for the treatment of status epilepticus.
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- Associated Conditions
- Agitation, Alcohol Withdrawal Delirium, Alcohol Withdrawal Syndrome, Anxiety, Anxiety Disorders, Chemotherapy-Induced Nausea and Vomiting, Delirium, Insomnia, Muscle Spasms, Panic Disorder, Psychogenic Catatonia, Status Epilepticus
- Associated Therapies
- Anesthetic premedication therapy
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Drug Development Updates
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