Cyclobenzaprine, a centrally-acting muscle relaxant, was first synthesized in 1961 and has been available for human use since 1977. It was initially studied for use as antidepressant given its structural similarity to tricyclic antidepressants - it differs from Amitriptyline by only a single double bond. Since its approval, it has remained relatively popular...
用于缓解与急性疼痛的肌肉骨骼疾病相关的肌肉痉挛(作为休息和物理治疗的辅助药)。但环苯扎林对脑、脊髓疾病或儿童脑性瘫痪引起的痉挛无效。
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