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Pirbuterol is a beta-2 adrenergic agonist and bronchodilator used for the symptomatic treatment of asthma.
Pirbuterol is a beta-2 adrenergic agonist and bronchodilator used for the symptomatic treatment of asthma.
The pharmacologic effects of beta adrenergic agonist drugs, including pirbuterol, are at least in proof attributable to stimulation through beta adrenergic receptors of intracellular adenyl cyclase, the enzyme which catalyzes the conversion of adenosine triphosphate (AlP) to cyclic-3† ,5†-adenosine monophosphate (c-AMP). Increased c-AMP levels are associated with relaxation of bronchial smooth muscle and inhibition of release of mediators of immediate hypersensitivity from cells, especially from mast cells.
For the prevention and reversal of bronchospasm in patients 12 years of age and older with reversible bronchospasm including asthma.
每项发明一条,涵盖美国、欧洲、PCT 与中国的同族专利。