MedPath

Octocrylene

Generic Name
Octocrylene
Brand Names
Meijer
Drug Type
Small Molecule
Chemical Formula
C24H27NO2
CAS Number
6197-30-4
Unique Ingredient Identifier
5A68WGF6WM

Overview

Octocrylene is a compound often used as an additive in sun screen, and is thought to have skin moisturizing effects because of its emollient properties. What makes this chemical such a popular additive to sun block, is its ability to neutralize UV radiation dissipated by sunlight, and to minimize skin damage from prolonged sun exposure. Octocrylene is also often combined with avobenzone, another common sunscreen ingredient often appearing on ingredient labels. Because of its effectiveness, the chemical has been approved across the globe for use in cosmetics and skin care products, but the concentrations of this ingredient are usually limited to no more than 10 or 12 percent. However, the use of this chemical doesn’t just stop with sunscreen for face and arms, but can extend to a variety of other products, like hair spray, tannin oil, BB cream, conditioner, and CC cream, among others. Octocrylene may cause contact and photocontact allergy.

Indication

In the US, Octocrylene has been evaluated by the FDA and is considered safe for use up to 10% in the formula. Similarly, the EU allows its use up to 10% in a formula while Health Canada allows a maximum use level of 12%.

Associated Conditions

  • Sunburn

Clinical Trials

Title
Posted
Study ID
Phase
Status
Sponsor

No clinical trials found

No clinical trials found for this drug

FDA Drug Approvals

Approved Product
Manufacturer
NDC Code
Route
Strength
Effective Date
Kenvue Brands LLC
69968-0601
TOPICAL
100 mg in 1 g
7/1/2025
Kenvue Brands LLC
69968-0828
TOPICAL
100 mg in 1 mL
7/1/2025
The Procter & Gamble Manufacturing Company
84126-153
TOPICAL
6 g in 100 g
6/9/2025
BENOW BEAUTY INC
85550-001
TOPICAL
5 g in 100 mL
4/14/2025
Valu Merchandisers
63941-929
TOPICAL
80 mg in 1 g
7/7/2025
OL PHARMA TECH LLC. (Drs. Pharmacy)
80489-235
TOPICAL
10 g in 100 g
3/24/2025
BEL STAR SA
14141-405
TOPICAL
100 mg in 1 mL
4/28/2025
Kenvue Brands LLC
69968-0816
TOPICAL
100 mg in 1 g
7/1/2025
Kenvue Brands LLC
69968-0702
TOPICAL
100 mg in 1 mL
7/1/2025
Murad, LLC
70381-131
TOPICAL
7.5 g in 100 mL
3/26/2025

EMA Drug Approvals

Approved Product
Authorization Holder
Status
Issued Date
No EMA approvals found for this drug.

HSA Drug Approvals

Approved Product
Manufacturer
Approval Number
Dosage Form
Strength
Approval Date
No HSA approvals found for this drug.

NMPA Drug Approvals

Approved Product
Company
Approval Number
Drug Type
Dosage Form
Approval Date
No NMPA approvals found for this drug.

PPB Drug Approvals

Approved Product
Registration No.
Company
Licence No.
Strength
Registration Date
No PPB approvals found for this drug.

Health Canada Drug Approvals

Approved Product
Company
DIN
Dosage Form
Strength
Market Date
BRIGHT BOOST MOISTURIZER SPF 30
johnson & johnson inc
02488116
Lotion - Topical
6 % / W/W
1/6/2020
BULL FROG WATER ARMOR SPORT QUICK SPRAY SUNSCREEN BROAD SPECTRUM SPF 50
sun & skin care research inc
02411113
Spray - Topical
2 % / W/W
N/A
BOTANICAL EFFECTS HYDRATE & PROTECT BROAD SPECTRUM SUNSCREEN SPF 30
mary kay cosmetics ltd
02401282
Lotion - Topical
2.0 % / W/W
N/A
BROAD SPECTRUM SPF 30 SPORT SUNSCREEN CONTINUOUS SPRAY
prime enterprises, llc
02397978
Spray, Bag-On-Valve - Topical
2.75 % / W/W
8/19/2013
OLAY COMPLETE 30 UVA/UVB 365 DAILY MOISTURIZING LOTION WITH SPF BROAD SPECTRUM SPF 30 SENSITIVE
procter & gamble inc
02461188
Lotion - Topical
2.5 % / W/W
1/1/2018
ROSALIAC UV LEGERE
laboratoires la roche-posay canada
02330792
Cream - Topical
4.6 % / W/W
6/16/2010
SHEER TOUCH TOUCHER SOYEUX OIL-FREE SUNSCREEN ÉCRAN SOLAIRE SANS HUILE SPF/FPS 50+
edgewell personal care canada, ulc
02454572
Lotion - Topical
6 %
10/6/2016
OLAY COMPLETE 15 UVA/UVB 365 DAILY MOISTURIZING LOTION WITH SPF BROAD SPECTRUM SPF 15 COMBINATION/OILY
procter & gamble inc
02461269
Lotion - Topical
2.6 %
10/1/2017
OLAY DEFINITY REFINING LOTION WITH UV PROTECTION
procter & gamble inc
02270587
Lotion - Topical
1 %
7/27/2006
OLAY PROFESSIONAL PRO-X AGE PROTECTION LOTION WITH SPF 30
procter & gamble inc
02310414
Lotion - Topical
2.25 % / W/W
2/5/2009

CIMA AEMPS Drug Approvals

Approved Product
Company
Registration Number
Pharmaceutical Form
Prescription Type
Status
No CIMA AEMPS (Spain) approvals found for this drug.

Philippines FDA Drug Approvals

Approved Product
Company
License Number
Dosage Form
Strength
Approval Date
No Philippines FDA approvals found for this drug.

Saudi SFDA Drug Approvals

Approved Product
Company
License Number
Dosage Form
Strength
Approval Date
No Saudi SFDA approvals found for this drug.

Malaysia NPRA Drug Approvals

Approved Product
Company
Registration Number
Dosage Form
Strength
Approval Date
No Malaysia NPRA approvals found for this drug.

UK EMC Drug Information

Medicine Name
MA Holder
MA Number
Pharmaceutical Form
Active Ingredient
Authorization Date
No UK EMC drug information found for this drug.

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