Medroxyprogesterone acetate

Generic Name: Medroxyprogesterone acetate

Brand Names: Depo-provera, Depo-subq Provera, Premphase 28 Day, Prempro 0.625/2.5 28 Day, Provera

Drug Type: Small Molecule

Chemical Formula: C_₂₄H_₃₄O_₄

CAS Number: 71-58-9

Unique Ingredient Identifier: C2QI4IOI2G

Background: Medroxyprogesterone acetate (MPA) is a progesterone derivative that is more resistant to metabolism for improved pharmacokinetic properties. MPA can be use to treat secondary amenorrhea, endometrial hyperplasia, abnormal uterine bleeding, osteoporosis, vasomotor symptoms in menopause, vulvar and vaginal atrophy, prevent pregnancy, manage pain in endometriosi...

Indication: Medroxyprogesterone acetate (MPA) oral tablets are indicated to treat secondary amenorrhea, reduce the incidence of endometrial hyperplasia in postmenopausal women, and to treat abnormal uterine bleeding due to hormonal imbalance, not organic pathology. Oral tablets containing MPA and conjugated estrogens are indicated to prevent postmenopausal osteoporosis ...

Associated Conditions: Abnormal Uterine Bleeding, Amenorrhea, Endometrial Hyperplasia, Endometriosis related pain, Metastatic Renal Cell Carcinoma ( mRCC), Osteoporosis, Pain, Postmenopausal Osteoporosis, Pregnancy, Vasomotor Symptoms Associated With Menopause, Vulvo Vaginal Atrophy, Metastatic Endometrial carcinoma

Associated Therapies: Contraception, Estrogen Replacement Therapy, Hormonal Contraception therapy

Clinical Trials

The Safety Lapses That Led Pfizer to Face Lawsuits Over Its Drugs

Pfizer faces lawsuits over Depo-Provera's link to meningiomas, Zantac's NDMA contamination leading to a $250 million settlement, and Protonix's alleged kidney damage. These cases highlight challenges in balancing pharmaceutical innovation with patient safety.

ktnv.com

a month ago

Nevada attorneys sue drug companies over birth control shot Depo-Provera

A woman suing Pfizer and generic drug manufacturers in Nevada's District Court over Depo-Provera, claiming it caused multiple brain tumors. Attorneys from Eglet LawGroup and Dimopoulos Law to discuss the case at 12 p.m. Monday.

health.clevelandclinic.org

2 months ago

Birth Control Gel: Effectiveness and How It Works

Birth control gel, Phexxi®, is an FDA-approved, hormone-free contraceptive inserted into the vagina. It works by maintaining an acidic environment that immobilizes sperm, preventing pregnancy. While typically effective (86% typical use, 93% perfect use), it may cause vaginal irritation and offers no STI protection. It's easy to use, on-demand, and can be combined with other contraceptive methods.

uc.edu

3 months ago

UC Cancer Center experts present research at ASTRO 2024

Meningiomas, brain or spinal cord tumors, can cause severe visual impairment. Progesterone, particularly in the form of Provera, was found to be a significant risk factor for vision loss related to meningiomas in premenopausal women. Researchers are now testing patient samples for progesterone receptor expression and have informed women taking Provera about the risks.

Drug Development Updates

Stay informed with timely notifications on clinical trials, regulatory changes, and research advancements related to this medication.

Home Terms & Conditions Privacy Policy