Medroxyprogesterone acetate

Generic Name
Medroxyprogesterone acetate
Brand Names
Depo-provera, Depo-subq Provera, Premphase 28 Day, Prempro 0.625/2.5 28 Day, Provera
Drug Type
Small Molecule
Chemical Formula
C24H34O4
CAS Number
71-58-9
Unique Ingredient Identifier
C2QI4IOI2G
Background

Medroxyprogesterone acetate (MPA) is a progesterone derivative that is more resistant to metabolism for improved pharmacokinetic properties. MPA can be use to treat secondary amenorrhea, endometrial hyperplasia, abnormal uterine bleeding, osteoporosis, vasomotor symptoms in menopause, vulvar and vaginal atrophy, prevent pregnancy, manage pain in endometriosi...

Indication

Medroxyprogesterone acetate (MPA) oral tablets are indicated to treat secondary amenorrhea, reduce the incidence of endometrial hyperplasia in postmenopausal women, and to treat abnormal uterine bleeding due to hormonal imbalance, not organic pathology. Oral tablets containing MPA and conjugated estrogens are indicated to prevent postmenopausal osteoporosis ...

Associated Conditions
Abnormal Uterine Bleeding, Amenorrhea, Endometrial Hyperplasia, Endometriosis related pain, Metastatic Renal Cell Carcinoma ( mRCC), Osteoporosis, Pain, Postmenopausal Osteoporosis, Pregnancy, Vasomotor Symptoms Associated With Menopause, Vulvo Vaginal Atrophy, Metastatic Endometrial carcinoma
Associated Therapies
Contraception, Estrogen Replacement Therapy, Hormonal Contraception therapy

Hormone Replacement Therapy and Anti-HIV Drugs in HIV-Infected, Postmenopausal Women

Phase 1
Terminated
Conditions
First Posted Date
2002-09-09
Last Posted Date
2015-06-04
Lead Sponsor
National Institute of Allergy and Infectious Diseases (NIAID)
Target Recruit Count
120
Registration Number
NCT00044837
Locations
🇺🇸

Barbara Brizz, Rockville, Maryland, United States

Depo-Medroxyprogesterone Acetate (DMPA, Depo-Provera) Use With Certain Anti-HIV Drugs in HIV-Infected Women

Not Applicable
Completed
Conditions
First Posted Date
2001-08-31
Last Posted Date
2012-11-02
Lead Sponsor
National Institute of Allergy and Infectious Diseases (NIAID)
Target Recruit Count
76
Registration Number
NCT00016601
Locations
🇺🇸

Univ of North Carolina, Chapel Hill, North Carolina, United States

🇺🇸

Univ of Southern California / LA County USC Med Ctr, Los Angeles, California, United States

🇺🇸

Indiana Univ Hosp, Indianapolis, Indiana, United States

and more 29 locations

Hormonal Birth Control and the Risk of Acquiring HIV

Not Applicable
Completed
Conditions
First Posted Date
2001-08-31
Last Posted Date
2008-08-07
Lead Sponsor
Eunice Kennedy Shriver National Institute of Child Health and Human Development (NICHD)
Target Recruit Count
6360
Registration Number
NCT00006324
Locations
🇺🇸

Amy Lovvorn, Research Triangle Park, North Carolina, United States

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