MedPath

Zilovertamab vedotin

Generic Name
Zilovertamab vedotin
Drug Type
Biotech
CAS Number
2376463-48-6
Unique Ingredient Identifier
IZY9ZSI6FI

Overview

Zilovertamab vedotin is an Antibody-drug conjugate (ADC) comprising an anti-ROR1 monoclonal antibody (UC-961), a proteolytically cleavable maleimidocaproyl-valine-citrulline-para-aminobenzoate linker (mc-vc-PAB), and a monomethyl auristatin E (MMAE) cytotoxin.

Background

Zilovertamab vedotin is an Antibody-drug conjugate (ADC) comprising an anti-ROR1 monoclonal antibody (UC-961), a proteolytically cleavable maleimidocaproyl-valine-citrulline-para-aminobenzoate linker (mc-vc-PAB), and a monomethyl auristatin E (MMAE) cytotoxin.

Indication

No indication information available.

Associated Conditions

No associated conditions information available.

Clinical Trials

Title
Posted
Study ID
Phase
Status
Sponsor
2025/03/24
Phase 2
Recruiting
2024/12/05
Phase 3
Recruiting
2024/05/01
Phase 1
Recruiting
2022/10/03
Phase 1
Active, not recruiting
2022/07/14
Phase 2
Recruiting
2022/06/06
Phase 2
Active, not recruiting
2021/12/01
Phase 2
Recruiting
2020/08/07
Phase 2
Terminated
VelosBio Inc., a subsidiary of Merck & Co., Inc. (Rahway, New Jersey USA)
2019/02/06
Phase 1
Completed
VelosBio Inc., a subsidiary of Merck & Co., Inc. (Rahway, New Jersey USA)

FDA Approved Products

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No FDA products found

No FDA products found for this drug

EMA Approved Products

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Issued
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No EMA products found

No EMA products found for this drug

Singapore Approved Products

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No Singapore products found

No Singapore products found for this drug

China Approved Products

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No China products found

No China products found for this drug

Australia Approved Products

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Ingredient

No Australia products found

No Australia products found for this drug

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