Heparin
- Generic Name
- Heparin
- Brand Names
- Heparin Leo
- Drug Type
- Small Molecule
- Chemical Formula
- -
- CAS Number
- 9005-49-6
- Unique Ingredient Identifier
- T2410KM04A
- Background
Unfractionated heparin (UH) is a heterogenous preparation of anionic, sulfated glycosaminoglycan polymers with weights ranging from 3000 to 30,000 Da. It is a naturally occurring anticoagulant released from mast cells. It binds reversibly to antithrombin III (ATIII) and greatly accelerates the rate at which ATIII inactivates coagulation enzymes thrombin (fac...
- Indication
Unfractionated heparin is indicated for prophylaxis and treatment of venous thrombosis and its extension, prevention of post-operative deep venous thrombosis and pulmonary embolism and prevention of clotting in arterial and cardiac surgery. In cardiology, it is used to prevent embolisms in patients with atrial fibrillation and as an adjunct antithrombin ther...
- Associated Conditions
- Blunt Injury, Clotting, Coagulopathy, Consumption, Contusions, Deep vein thrombosis postoperative, Disseminated Intravascular Coagulation (DIC), External Hemorrhoid, Inflammation, Inflammatory, non-infectious pruritic dermatosis, Interstitial Cystitis, Post procedural pulmonary embolism, Pulmonary Embolism, ST Segment Elevation Myocardial Infarction (STEMI), Sprains, Thromboembolism, Unstable Angina Pectoris, Venous Thrombosis (Disorder), Hematomas, Peripheral arterial embolism, Thromboembolic phenomena, Varicosities of the great saphenous vein
- Associated Therapies
- Circulation, Extracorporeal, Dialysis therapy, Transfusions, Maintenance of patency of IV injection devices
Comparison of Anticoagulation Prolongation vs. no Anticoagulation in STEMI Patients After Primary PCI
- First Posted Date
- 2018-09-10
- Last Posted Date
- 2023-05-03
- Lead Sponsor
- Beijing Anzhen Hospital
- Target Recruit Count
- 2989
- Registration Number
- NCT03664180
- Locations
- 🇨🇳
Beijing Anzhen Hospital, Capital Medical University, Beijing, China
Heparin Intraoperative Instillation for Lower Urinary Tract Symptoms After Benign Hysterectomy
- Conditions
- Interventions
- First Posted Date
- 2018-08-16
- Last Posted Date
- 2019-10-10
- Lead Sponsor
- The Christ Hospital
- Target Recruit Count
- 104
- Registration Number
- NCT03633994
- Locations
- 🇺🇸
The Christ Hospital, Cincinnati, Ohio, United States
Taurolock Hep 500 Versus Unfractionated Heparin as Anti-inflammatory in Hemodialysis Catheters.
- Conditions
- Interventions
- First Posted Date
- 2018-05-29
- Last Posted Date
- 2018-05-29
- Lead Sponsor
- Ain Shams University
- Target Recruit Count
- 60
- Registration Number
- NCT03539718
- Locations
- 🇪🇬
Ain Shams University Hospitals, Cairo, Egypt
A Single Center Diagnostic, Cross-sectional Study of Coronary Microvascular Dysfunction
- Conditions
- Interventions
- First Posted Date
- 2018-05-25
- Last Posted Date
- 2024-01-11
- Lead Sponsor
- NYU Langone Health
- Target Recruit Count
- 165
- Registration Number
- NCT03537586
- Locations
- 🇺🇸
New York University School of Medicine, New York, New York, United States
Acute Mesenteric Venous Thrombosis.. in Assiut University Hospital Management Controversies
- Conditions
- Interventions
- First Posted Date
- 2018-03-30
- Last Posted Date
- 2018-03-30
- Lead Sponsor
- Assiut University
- Target Recruit Count
- 30
- Registration Number
- NCT03483207
Streptokinase Versus Unfractionated Heparin Nebulization in Severe ARDS
- Conditions
- Interventions
- First Posted Date
- 2018-03-14
- Last Posted Date
- 2018-03-14
- Lead Sponsor
- Beni-Suef University
- Target Recruit Count
- 60
- Registration Number
- NCT03465085
Comparision Between Activated Partial Thromboplastin Time Versus Anti-Xa Activity in Heparin Monitoring
- Conditions
- Interventions
- First Posted Date
- 2018-02-09
- Last Posted Date
- 2018-03-14
- Lead Sponsor
- Wuhan Asia Heart Hospital
- Target Recruit Count
- 700
- Registration Number
- NCT03426982
- Locations
- 🇨🇳
Wuhan Asia Heart Hospital, Wuhan, Hubei, China
Neutrolin Versus Heparin for Locking Hemodialysis Catheters
- Conditions
- Interventions
- First Posted Date
- 2018-02-07
- Last Posted Date
- 2019-03-05
- Target Recruit Count
- 192
- Registration Number
- NCT03425448
TIPS or Anticoagulation in Portal Vein Thrombosis
- First Posted Date
- 2018-02-05
- Last Posted Date
- 2018-11-01
- Lead Sponsor
- Insel Gruppe AG, University Hospital Bern
- Registration Number
- NCT03422419
Heparin Anticoagulation in Septic Shock
- Conditions
- Interventions
- First Posted Date
- 2017-12-19
- Last Posted Date
- 2022-05-24
- Lead Sponsor
- University of Manitoba
- Target Recruit Count
- 178
- Registration Number
- NCT03378466
- Locations
- 🇧🇷
Hospital da Cidade, Salvador, Brazil
🇨🇦The Ottawa Hospital - Civic Campus, Ottawa, Ontario, Canada
🇧🇷Hospital Tacchini, Bento Gonçalves, Brazil
Drug Development Updates
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